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Table 2 Sex differences in therapeutic options for CVDs

From: Sex-specific influence on cardiac structural remodeling and therapy in cardiovascular disease

Therapeutic option Effect
Statins M = F [78], but F higher risk of adverse drug reaction
ACE inhibitors M = F [74]
Angiotensin receptor blockers and β-blockers M = F, but F slower clearance, lower volume of distribution, and less sensitive [74]
ICD M = F [76, 77]
Calcium channel blockers F faster clearance of, e.g., verapamil and nifedipine, but faster reduction of blood pressure [74]
  1. Abbreviations: F = female; M = male; ACE = angiotensin-converting enzyme; ICD = implantable cardiac defibrillator