Sex-specific influence on cardiac structural remodeling and therapy in cardiovascular disease

Table 2 Sex differences in therapeutic options for CVDs

Therapeutic option	Effect
Statins	M = F [78], but F higher risk of adverse drug reaction
ACE inhibitors	M = F [74]
Angiotensin receptor blockers and β-blockers	M = F, but F slower clearance, lower volume of distribution, and less sensitive [74]
ICD	M = F [76, 77]
Calcium channel blockers	F faster clearance of, e.g., verapamil and nifedipine, but faster reduction of blood pressure [74]

Abbreviations: F = female; M = male; ACE = angiotensin-converting enzyme; ICD = implantable cardiac defibrillator

ISSN: 2042-6410