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Table 2 Statistical analysis of data presented in Fig. 3. Post hoc results are only shown for tests which reached statistical significance (P < 0.05)

From: Estrogen receptor profiles across tissues from male and female Rattus norvegicus

  DF eta squared Cohen’s d F (DFn, DFd) t P value
Adrenal (two-way)
 Interaction 2 1.309 F (2, 29) = 3.298 P = 0.0512
 Sex 1 0.8823 F (1, 29) = 4.445 P = 0.0438
 >ESR1: F vs. M 29 1.24 t = 3.347 P = 0.0068
 gene 2 91.78 F (2, 29) = 231.2 P < 0.0001
 >F: GPER vs. ESR1 29 − 9.530 t = 13.15 P < 0.0001
 >F: GPER vs. ESR2 29 8.580 t = 3.079 P = 0.0135
 >F: ESR1 vs. ESR2 29 15.81 t = 16.23 P < 0.0001
 >M: GPER vs. ESR1 29 − 4.442 t = 10.17 P < 0.0001
 >M: GPER vs. ESR2 29 4.313 t = 2.591 P = 0.0438
 >M: ESR1 vs. ESR2 29 7.654 t = 12.29 P < 0.0001
Aorta (two-way)
 Interaction 2 5.10 F (2, 29) = 6.87 P = 0.0036
 Sex 1 2.77 F (1, 29) = 7.47 P = 0.0106
 >ESR1: F vs. M 29 − 4.60 t = 4.66 P = 0.0002
 Gene 2 81.0 F (2, 29) = 109 P < 0.0001
 >F: GPER vs. ESR1 29 − 2.72 t = 6.27 P < 0.0001
 >F: ESR1 vs. ESR2 29 3.33 t = 7.34 P < 0.0001
 >M: GPER vs. ESR1 29 − 7.31 t = 10.8 P < 0.0001
 >M: ESR1 vs. ESR2 29 8.74 t = 11.4 P < 0.0001
Heart (two-way)
 Interaction 2 0.769 F (2, 30) = 0.804 P = 0.457
 Sex 1 0.0665 F (1, 30) = 0.139 P = 0.712
 Gene 2 84.8 F (2, 30) = 88.7 P < 0.0001
 >F: GPER vs. ESR1 30 − 2.87 t = 4.76 P = 0.0001
 >F: GPER vs. ESR2 30 4.29 t = 4.88 P < 0.0001
 >F: ESR1 vs. ESR2 30 17.2 t = 9.64 P < 0.0001
 >M: GPER vs. ESR1 30 − 1.29 t = 3.01 P = 0.0157
 >M: GPER vs. ESR2 30 7.12 t = 6.09 P < 0.0001
 >M: ESR1 vs. ESR2 30 6.05 t = 9.10 P < 0.0001
Kidney
 Interaction 2 18.6 F (2, 30) = 0.804 P < 0.0001
 Sex 1 7.30 F (1, 30) = 0.139 P = 0.0002
 >ESR1: F vs. M 30 − 3.08 t = 8.09 P < 0.0001
 Gene 2 62.3 F (2, 30) = 88.7 P < 0.0001
 >F: GPER vs. ESR1 30 − 2.81 t = 4.76 P = 0.023
 >F: ESR1 vs. ESR2 30 6.18 t = 9.64 P = 0.0009
 >M: GPER vs. ESR1 30 − 5.25 t = 3.01 P < 0.0001
 >M: ESR1 vs. ESR2 30 6.16 t = 9.10 P < 0.0001