Table 2 Statistical analysis of data presented in Fig. 3. Post hoc results are only shown for tests which reached statistical significance (P < 0.05)
From: Estrogen receptor profiles across tissues from male and female Rattus norvegicus
|  | DF | eta squared Cohen’s d | F (DFn, DFd) t | P value |
|---|---|---|---|---|
Adrenal (two-way) | ||||
 Interaction | 2 | 1.309 | F (2, 29) = 3.298 | P = 0.0512 |
 Sex | 1 | 0.8823 | F (1, 29) = 4.445 | P = 0.0438 |
 >ESR1: F vs. M | 29 | 1.24 | t = 3.347 | P = 0.0068 |
 gene | 2 | 91.78 | F (2, 29) = 231.2 | P < 0.0001 |
 >F: GPER vs. ESR1 | 29 | − 9.530 | t = 13.15 | P < 0.0001 |
 >F: GPER vs. ESR2 | 29 | 8.580 | t = 3.079 | P = 0.0135 |
 >F: ESR1 vs. ESR2 | 29 | 15.81 | t = 16.23 | P < 0.0001 |
 >M: GPER vs. ESR1 | 29 | − 4.442 | t = 10.17 | P < 0.0001 |
 >M: GPER vs. ESR2 | 29 | 4.313 | t = 2.591 | P = 0.0438 |
 >M: ESR1 vs. ESR2 | 29 | 7.654 | t = 12.29 | P < 0.0001 |
Aorta (two-way) | ||||
 Interaction | 2 | 5.10 | F (2, 29) = 6.87 | P = 0.0036 |
 Sex | 1 | 2.77 | F (1, 29) = 7.47 | P = 0.0106 |
 >ESR1: F vs. M | 29 | − 4.60 | t = 4.66 | P = 0.0002 |
 Gene | 2 | 81.0 | F (2, 29) = 109 | P < 0.0001 |
 >F: GPER vs. ESR1 | 29 | − 2.72 | t = 6.27 | P < 0.0001 |
 >F: ESR1 vs. ESR2 | 29 | 3.33 | t = 7.34 | P < 0.0001 |
 >M: GPER vs. ESR1 | 29 | − 7.31 | t = 10.8 | P < 0.0001 |
 >M: ESR1 vs. ESR2 | 29 | 8.74 | t = 11.4 | P < 0.0001 |
Heart (two-way) | ||||
 Interaction | 2 | 0.769 | F (2, 30) = 0.804 | P = 0.457 |
 Sex | 1 | 0.0665 | F (1, 30) = 0.139 | P = 0.712 |
 Gene | 2 | 84.8 | F (2, 30) = 88.7 | P < 0.0001 |
 >F: GPER vs. ESR1 | 30 | − 2.87 | t = 4.76 | P = 0.0001 |
 >F: GPER vs. ESR2 | 30 | 4.29 | t = 4.88 | P < 0.0001 |
 >F: ESR1 vs. ESR2 | 30 | 17.2 | t = 9.64 | P < 0.0001 |
 >M: GPER vs. ESR1 | 30 | − 1.29 | t = 3.01 | P = 0.0157 |
 >M: GPER vs. ESR2 | 30 | 7.12 | t = 6.09 | P < 0.0001 |
 >M: ESR1 vs. ESR2 | 30 | 6.05 | t = 9.10 | P < 0.0001 |
Kidney | ||||
 Interaction | 2 | 18.6 | F (2, 30) = 0.804 | P < 0.0001 |
 Sex | 1 | 7.30 | F (1, 30) = 0.139 | P = 0.0002 |
 >ESR1: F vs. M | 30 | − 3.08 | t = 8.09 | P < 0.0001 |
 Gene | 2 | 62.3 | F (2, 30) = 88.7 | P < 0.0001 |
 >F: GPER vs. ESR1 | 30 | − 2.81 | t = 4.76 | P = 0.023 |
 >F: ESR1 vs. ESR2 | 30 | 6.18 | t = 9.64 | P = 0.0009 |
 >M: GPER vs. ESR1 | 30 | − 5.25 | t = 3.01 | P < 0.0001 |
 >M: ESR1 vs. ESR2 | 30 | 6.16 | t = 9.10 | P < 0.0001 |