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Table 2 Demographic and clinical characteristics of the study subjects according to sex-specific type of plaques

From: Sex-related differences in the association between plasma fibrinogen and non-calcified or mixed coronary atherosclerotic plaques

Variables

Male

Female

NP (n = 39)

CP (n = 74)

NCP/MP (n = 92)

P

NP (n = 40)

CP (n = 46)

NCP/MP (n = 38)

P

Age (years)

48.5 ± 8.8

58.8 ± 9.8

57.5 ± 9.6

< 0.001

51.6 ± 9.3

65.5 ± 7.2

59.9 ± 9.7

< 0.001

BMI (kg/m2)

26.4 ± 3.0

25.7 ± 3.6

26.4 ± 4.1

0.470

23.7 ± 3.2

25.3 ± 3.6

24.5 ± 3.0

0.100

Hypertension, n (%)

18 (46.2%)

49 (66.2%)

60 (65.2%)

0.077

10 (25.0%)

32 (69.6%)

24 (63.2%)

< 0.001

Diabetes, n (%)

7 (17.9%)

20 (27.0%)

29 (31.5%)

0.280

5 (12.5%)

9 (19.6%)

12 (31.6%)

0.113

Dyslipidemia, n (%)

22 (56.4%)

61 (82.4%)

81 (88.0%)

< 0.001

17 (42.5%)

33 (71.7%)

33 (86.8%)

< 0.001

Smoking, n (%)

15 (38.5%)

29 (39.2%)

40 (43.5%)

0.803

1 (2.5%)

2 (4.3%)

3 (7.9%)

0.530

Alcohol consumption, n (%)

22 (56.4%)

36 (48.6%)

41 (44.6%)

0.462

2 (5.0%)

2 (4.3%)

1 (2.6%)

0.860

History of CAD, n (%)

6 (15.4%)

9 (12.2%)

11 (12.0%)

0.853

6 (15.0%)

6 (13.0%)

6 (15.8%)

0.934

Biochemical parameters

 TC (mmol/L)

5.03 ± 0.87

4.36 ± 1.03

4.35 ± 1.22

0.003

4.87 ± 0.96

5.00 ± 1.90

5.11 ± 1.32

0.765

 TG (mmol/L)

1.83 (1.34, 2.43)

1.56 (1.09, 2.18)

1.53 (1.16, 2.14)

0.226

1.43 (0.90, 1.86)

1.49 (0.97, 2.18)

1.87 (1.20, 2.56)

0.079

 HDL-C (mmol/L)

1.11 ± 0.29

1.13 ± 0.29

1.06 ± 0.27

0.328

1.28 ± 0.40

1.33 ± 0.34

1.20 ± 0.27

0.185

 LDL-C (mmol/L)

3.14 ± 0.83

2.58 ± 0.87

2.65 ± 0.97

0.006

3.01 ± 0.72

2.86 ± 0.87

3.10 ± 1.00

0.441

 hsCRP (mg/L)

1.45 (0.94, 1.92)

1.24 (0.60, 2.97)

1.44 (0.80, 2.90)

0.649

0.98 (0.43, 2.36)

1.50 (0.85, 2.40)

1.83 (0.89, 4.37)

0.029

 FIB (g/L)

3.00 ± 0.61

2.96 ± 0.52

3.16 ± 0.80

0.161

3.18 ± 0.75

3.23 ± 0.51

3.68 ± 0.61

0.001

Medications, n (%)

 Statins

15 (38.5%)

53 (71.6%)

74 (80.4%)

< 0.001

15 (37.5%)

30 (65.2%)

26 (68.4%)

0.009

 Aspirin

21 (53.8%)

57 (77.0%)

79 (85.9%)

< 0.001

16 (40.0%)

38 (82.6%)

28 (73.7%)

< 0.001

 Calcium antagonists

9 (23.1%)

32 (43.2%)

28 (30.4%)

0.066

4 (10.0%)

24 (52.2%)

11 (28.9%)

< 0.001

 ARB/ACEI

13 (33.3%)

31 (41.9%)

49 (53.3%)

0.084

4 (10.0%)

18 (39.1%)

12 (31.6%)

0.008

 Beta-blockers

11 (28.2%)

42 (56.8%)

49 (53.3%)

0.010

13 (32.5%)

20 (43.5%)

21 (55.3%)

0.128

 Diuretics

2 (5.1%)

21 (28.4%)

22 (23.9%)

0.015

4 (10.0%)

7 (15.2%)

6 (15.8%)

0.707