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Table 2 Demographic and clinical characteristics of the study subjects according to sex-specific type of plaques

From: Sex-related differences in the association between plasma fibrinogen and non-calcified or mixed coronary atherosclerotic plaques

Variables Male Female
NP (n = 39) CP (n = 74) NCP/MP (n = 92) P NP (n = 40) CP (n = 46) NCP/MP (n = 38) P
Age (years) 48.5 ± 8.8 58.8 ± 9.8 57.5 ± 9.6 < 0.001 51.6 ± 9.3 65.5 ± 7.2 59.9 ± 9.7 < 0.001
BMI (kg/m2) 26.4 ± 3.0 25.7 ± 3.6 26.4 ± 4.1 0.470 23.7 ± 3.2 25.3 ± 3.6 24.5 ± 3.0 0.100
Hypertension, n (%) 18 (46.2%) 49 (66.2%) 60 (65.2%) 0.077 10 (25.0%) 32 (69.6%) 24 (63.2%) < 0.001
Diabetes, n (%) 7 (17.9%) 20 (27.0%) 29 (31.5%) 0.280 5 (12.5%) 9 (19.6%) 12 (31.6%) 0.113
Dyslipidemia, n (%) 22 (56.4%) 61 (82.4%) 81 (88.0%) < 0.001 17 (42.5%) 33 (71.7%) 33 (86.8%) < 0.001
Smoking, n (%) 15 (38.5%) 29 (39.2%) 40 (43.5%) 0.803 1 (2.5%) 2 (4.3%) 3 (7.9%) 0.530
Alcohol consumption, n (%) 22 (56.4%) 36 (48.6%) 41 (44.6%) 0.462 2 (5.0%) 2 (4.3%) 1 (2.6%) 0.860
History of CAD, n (%) 6 (15.4%) 9 (12.2%) 11 (12.0%) 0.853 6 (15.0%) 6 (13.0%) 6 (15.8%) 0.934
Biochemical parameters
 TC (mmol/L) 5.03 ± 0.87 4.36 ± 1.03 4.35 ± 1.22 0.003 4.87 ± 0.96 5.00 ± 1.90 5.11 ± 1.32 0.765
 TG (mmol/L) 1.83 (1.34, 2.43) 1.56 (1.09, 2.18) 1.53 (1.16, 2.14) 0.226 1.43 (0.90, 1.86) 1.49 (0.97, 2.18) 1.87 (1.20, 2.56) 0.079
 HDL-C (mmol/L) 1.11 ± 0.29 1.13 ± 0.29 1.06 ± 0.27 0.328 1.28 ± 0.40 1.33 ± 0.34 1.20 ± 0.27 0.185
 LDL-C (mmol/L) 3.14 ± 0.83 2.58 ± 0.87 2.65 ± 0.97 0.006 3.01 ± 0.72 2.86 ± 0.87 3.10 ± 1.00 0.441
 hsCRP (mg/L) 1.45 (0.94, 1.92) 1.24 (0.60, 2.97) 1.44 (0.80, 2.90) 0.649 0.98 (0.43, 2.36) 1.50 (0.85, 2.40) 1.83 (0.89, 4.37) 0.029
 FIB (g/L) 3.00 ± 0.61 2.96 ± 0.52 3.16 ± 0.80 0.161 3.18 ± 0.75 3.23 ± 0.51 3.68 ± 0.61 0.001
Medications, n (%)
 Statins 15 (38.5%) 53 (71.6%) 74 (80.4%) < 0.001 15 (37.5%) 30 (65.2%) 26 (68.4%) 0.009
 Aspirin 21 (53.8%) 57 (77.0%) 79 (85.9%) < 0.001 16 (40.0%) 38 (82.6%) 28 (73.7%) < 0.001
 Calcium antagonists 9 (23.1%) 32 (43.2%) 28 (30.4%) 0.066 4 (10.0%) 24 (52.2%) 11 (28.9%) < 0.001
 ARB/ACEI 13 (33.3%) 31 (41.9%) 49 (53.3%) 0.084 4 (10.0%) 18 (39.1%) 12 (31.6%) 0.008
 Beta-blockers 11 (28.2%) 42 (56.8%) 49 (53.3%) 0.010 13 (32.5%) 20 (43.5%) 21 (55.3%) 0.128
 Diuretics 2 (5.1%) 21 (28.4%) 22 (23.9%) 0.015 4 (10.0%) 7 (15.2%) 6 (15.8%) 0.707