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Table 3 Expression of genes coding for cannabinoid receptors (CB1–CNR1, CB2–CNR2), S100A6 and CacyBP/SIP in male and female hearts

From: Sex differences in distribution of cannabinoid receptors (CB1 and CB2), S100A6 and CacyBP/SIP in human ageing hearts

Group of patients

 

Expression of genes

No. of patients

CB1

CB2

S100A6

CacyBP/SIP

Under 50 years old

Overall

11

1.5 ± 0.50

1.2 ± 0.39

0.8 ± 0.21

0.7 ± 0.16

Men

6

1.3 ± 0.50

1.5 ± 0.42

0.9 ± 0.18

0.7 ± 0.21

 

Women

5

1.9 ± 0.20

1.0 ± 0.05

0.6 ± 0.11

0.7 ± 0.08

   

 

Over 50 years old

Overall

11

0.8 ± 0.15*

0.8 ± 0.10*

2.2 ± 0.81*

1.4 ± 0.35*

Men

6

0.9 ± 0.14*

0.7 ± 0.08*

2.9 ± 0.47*

1.1 ± 0.21*

 

Women

5

0.7 ± 0.09*

0.9 ± 0.08*

1.5 ± 0.24*

1.7 ± 0.17*

   

↓* ↓

↓* ↑

↑* ↓

↑* ↑

  1. Data present mean ± SE
  2. *p < 0.05 patients over 50 vs patients under 50 years old
  3. p < 0.05 women vs men belonging to the same age group