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Table 2 Intensity of immunoreaction against cannabinoid receptors (CB1, CB2), S100A6, CacyBP/SIP, in men and women hearts (scale from 0 (black pixel) to 256 (white pixel))

From: Sex differences in distribution of cannabinoid receptors (CB1 and CB2), S100A6 and CacyBP/SIP in human ageing hearts

Group of patients

No. of measurements

Intensity of immunohistochemical reaction in the men heart

CB1

CB2

S100A6

CacyBP/SIP

Cardiomyocyte

cytoplasm

Intercalated

discs

Cardiomyocyte

cytoplasm

Cardiomyocyte

cytoplasm

Cardiomyocyte

cytoplasm

Under 50 years old

Men

2250

136.1 ± 1.76

ND

148.1 ± 1.75

162.0 ± 2.83

172.3 ± 1.90

Women

1875

118.8 ± 2.87

ND

167.6 ± 2.64

177.3 ± 1.79

171.7 ± 2.89

   

 

 

Over 50 years old

Men

2250

142.0 ± 1.72*

79.5 ± 3.32*

186.3 ± 2.91*

132.4 ± 2.56*

152.4 ± 1.85*

Women

1875

155.6 ± 2.53*

86.9 ± 4.71*

177.5 ± 3.45*

150.1 ± 2.93*

147.0 ± 1.82*

   

↓* ↓

↑*

↓* ↑

↑* ↓

↑* ↑

  1. Data present mean ± SE
  2. *p < 0.05 patients over 50 vs patients under 50 years old
  3. p < 0.05 women vs men belonging to the same age group
  4. Weaker immunohistochemical reaction
  5. More intense immunohistochemical reaction
  6. ND not detected