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Table 2 Intensity of immunoreaction against cannabinoid receptors (CB1, CB2), S100A6, CacyBP/SIP, in men and women hearts (scale from 0 (black pixel) to 256 (white pixel))

From: Sex differences in distribution of cannabinoid receptors (CB1 and CB2), S100A6 and CacyBP/SIP in human ageing hearts

Group of patients No. of measurements Intensity of immunohistochemical reaction in the men heart
CB1 CB2 S100A6 CacyBP/SIP
Cardiomyocyte
cytoplasm
Intercalated
discs
Cardiomyocyte
cytoplasm
Cardiomyocyte
cytoplasm
Cardiomyocyte
cytoplasm
Under 50 years old Men 2250 136.1 ± 1.76 ND 148.1 ± 1.75 162.0 ± 2.83 172.3 ± 1.90
Women 1875 118.8 ± 2.87 ND 167.6 ± 2.64 177.3 ± 1.79 171.7 ± 2.89
       
Over 50 years old Men 2250 142.0 ± 1.72* 79.5 ± 3.32* 186.3 ± 2.91* 132.4 ± 2.56* 152.4 ± 1.85*
Women 1875 155.6 ± 2.53* 86.9 ± 4.71* 177.5 ± 3.45* 150.1 ± 2.93* 147.0 ± 1.82*
    ↓* ↓ ↑* ↓* ↑ ↑* ↓ ↑* ↑
  1. Data present mean ± SE
  2. *p < 0.05 patients over 50 vs patients under 50 years old
  3. p < 0.05 women vs men belonging to the same age group
  4. Weaker immunohistochemical reaction
  5. More intense immunohistochemical reaction
  6. ND not detected