Fig. 7
From: Sexually dimorphic metabolic responses mediated by CRF2 receptor during nutritional stress in mice
Male mice have increased plasma lipid levels. Column bar graphs show plasma lipid profiles in male and female mice. Plasma cholesterol, HDL, triglycerides, and LDL levels were determined. a HFD-fed male WT and Crhr2−/− mice had 37.7%, and 40.9% higher blood cholesterol levels vs. chow diet, respectively. b In female WT and Crhr2−/− mice, HFD consumption resulted in smaller, non-significant increases in blood cholesterol levels vs. chow. c HFD-fed male WT mice had 36.1% higher HDL levels vs. chow. d In female mice, HDL levels did not differ between HFD vs. chow. e HFD-fed male Crhr2−/− mice had ~ 53.0% higher calculated LDL levels vs. chow-fed Crhr2−/− and HFD-fed WT mice. f In female mice, diet did not change LDL levels. g, h In male and female mice, diet did not change triglycerides levels. n = 8/group/sex. Three-way ANOVA and post hoc Tukey’s multiple comparisons