Table 1 Overlap between sex-specific NAFLD subnetworks and DEGs affected by sex hormones
Tissue | Sex | Network size | DEG size | Overlap gene size (overlap KD size) | Overlap KD list | Fold change | P value |
|---|---|---|---|---|---|---|---|
Liver | M | 218 | 2435 | 100 (14) | C8B, CYP7B1, SLC16A7, SLC16A5, CD36, MGST3, NCKAP1L, INPP5D, ANXA2, HCK, FCER1G, FGL2, CIDEC, TBC1D15 | 6.13 | 8.28E−71 |
F | 86 | 196 | 2 (0) | – | 3.86 | 8.68E−02 | |
Adipose | M | 261 | 1804 | 71 (8) | FASN, AACS, ETFDH, GYS1, ECHS1, SH3D21, SLC2A3, PMEPA1 | 4.39 | 9.34E−35 |
F | 206 | 1491 | 34 (5) | MSLN, GPM6A, PTGIS, RSPO1, BNC1 | 3.22 | 4.57E−13 |