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Fig. 7 | Biology of Sex Differences

Fig. 7

From: Sex-specific differences in hepatic steatosis in obese spontaneously hypertensive (SHROB) rats

Fig. 7

Quantification of gender-specific differences in hepatic gene expression by qPCR in SHROB rats. The relative mRNA levels were normalized against Rn18s RNA and compared with WT female set as 1. N = 3 for each group. Statistical significance: *p < 0.05, **p < 0.01. a Genes related to gender differences including peroxisome proliferator-activated receptor gamma (Pparg), peroxisome proliferator-activated receptor alpha (Ppara), cluster of differentiation 36 (Cd36), solute carrier family 2 member 4 (Slc2a4), antioxidant protein 1 (Atox1), S-phase kinase-associated protein 1 (Skp1), angiopoietin-like 3 (Angptl3), and papatin-like phospholipase domain-containing protein 3 (Pnpla3). b Genes related to lipogenesis including sterol regulatory element-binding transcription factor 1 (Srebf1), acetyl-CoA carboxylase alpha (Acaca), acetyl-CoA carboxylase beta (Acacb), stearoyl-CoA desaturase (Scd), fatty acid synthesis (Fasn), and ATP citrate lyase (Acly)

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