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Table 2 Measures of peripheral mitochondrial function and cerebral metabolism

From: Sex-associated differences in mitochondrial function in human peripheral blood mononuclear cells (PBMCs) and brain

  Women
n = 15
Men
n = 9
p value η 2
O2k-Oxygraph
[pmol/(s*IU CS)]
 Endogenous 205.8 ± 12.4 145 ± 14.8 0.007** 0.40
 CI 453.6 ± 36.0 313 ± 39.6 0.02* 0.30
 CI+II 1096.0 ± 86.4 814.5 ± 76.1 0.03* 0.27
 ETS 1028 ± 94.8 772.2 ± 69.1 0.04* 0.22
 CIIETS 612.8 ± 42.3 448.5 ± 34.5 0.008** 0.36
 CIV 1495 ± 104.6 1045 ± 85.12 0.004** 0.40
 CS activity [IU/106 cells] 0.2914 ± 0.019 0.2211 ± 0.025 0.04* 0.29
 ATP levels [μM/105 cells] 2.50 ± 0.2 2.20 ± 0.3 0.45 0.04
 NAA in GM [mmol/l] 12.27 ± 0.19 11.35 ± 0.25 0.009** 0.35
 NAA in WM [mmol/l] 14.79 ± 0.38 13.32 ± 0.40 0.01* 0.25
  1. Mean ± SEM, unpaired t test with Welch’s correction, significant differences are marked by asterisk, (*p<0.05; **p<0.01)
  2. ATP adenosine triphosphate, CS citrate synthase, C complex, ETS electron transport system, GM gray matter, NAA N-acetylaspartate, WM white matter