Fig. 1
From: Sex and strain dependent differences in mucosal immunology and microbiota composition in mice
Effect of sex and strain on fecal microbiota characteristics. Shannon diversity (a), richness (b), and the Firmicutes/Bacteroidetes (c) ratio in the fecal microbiota of male and female BALB/c and B6 mice (5 mice per group). Results are shown as mean + SEM and were tested for overall strain and sex effects using a two-way ANOVA followed by a Bonferroni post hoc test to test for strain-specific sex effects when interaction was found. Significant strain effects are indicated with solid lines and significant sex effects are indicated with dashed lines (p < 0.05). RDA plot showing the variation explained by the components genotype and sex (five mice per group) (d). The total variation that can be explained by the variables genotype (26.5%) and sex (11.6%) is 38.1%. Both variables are significant in explaining the variation (Monte Carlo permutation, p < 0.05)