Table 1 Hemodynamic assessment of AngII-treated (2 mg/kg/day) female GPR37L1^wt/wt and GPR37L1^KO/KO mice by micromanometry under anesthesia

HR (bpm)

515.6 ± 8.0

512.3 ± 7.1

− 3.3

504.4 ± 6.8

503.6 ± 3.6

− 0.8

SP (mmHg)

109.3 ± 3.3

135.5 ± 4.1*

26.2

119.7 ± 6.3

130.9 ± 3.7

11.2

DP (mmHg)

78.1 ± 2.3

83.7 ± 2.5

5.6

83.1 ± 2.8

86.8 ± 2.4

3.7

MAP (mmHg)

88.5 ± 2.6

101 ± 2.8*

12.5

95.3 ± 3.9

101.5 ± 2.7

6.2

PP (mmHg)

31.2 ± 1.2

51.8 ± 3.0*

20.6

36.6 ± 3.6

44.0 ± 2.2

7.4

HR (bpm)

500.9 ± 8.2

500.4 ± 2.2

− 0.5

514.0 ± 9.6

508.9 ± 4.8

− 5.1

SP (mmHg)

106.5 ± 3.1

128.8 ± 1.5*

22.3

112.9 ± 4.7

126.4 ± 2.6*

13.5

EDP (mmHg)

6.4 ± 0.5

7.0 ± 1.1

0.6

5.3 ± 0.3

8.7 ± 1.1*

3.4

dP/dT max (mmHg/s)

9799 ± 860.0

10,998 ± 426.2

1199

11,343 ± 745

12,455 ± 383.9

1112

dP/dT min (mmHg/s)

− 9019 ± 853.7

− 9253 ± 584.0

− 234

− 9262 ± 470.2

− 9718 ± 330.8

− 456

Body weight (g)

21.2 ± 0.3

22.3 ± 0.3

1.1

23.3 ± 0.5

22.3 ± 0.3

−1.0

Tibia length (mm)

16.1 ± 0.1

16.1 ± 0.1

0

16.4 ± 0.1

16.4 ± 0.1

0

HW:TL (mg/mm)

6.5 ± 0.1

8.1 ± 0.2*

1.6

6.8 ± 0.1

8.2 ± 0.2*

1.4

LVW:TL (mg/mm)

4.6 ± 0.1

6.0 ± 0.2*

1.4

4.9 ± 0.1

6.2 ± 0.1*

1.3

RVW:TL (mg/mm)

1.4 ± 0.0

1.4 ± 0.0

0

1.4 ± 0.0

1.4 ± 0.0

0

Lung:TL (mg/mm)

9.9 ± 0.4

9.5 ± 0.3

− 0.4

9.3 ± 0.5

9.7 ± 0.4

0.4