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Fig. 3 | Biology of Sex Differences

Fig. 3

From: Orphan receptor GPR37L1 contributes to the sexual dimorphism of central cardiovascular control

Fig. 3

Male GPR37L1KO/KO mice have an exacerbated response to AngII infusion. Effect of 7 days AngII infusion (2 mg/kg/day) on male and female GPR37L1wt/wt and GPR37L1KO/KO mice (10–12 weeks old). a Left ventricle (LV) weight normalized to tibia length. n ≥ 15. b Cardiomyocyte hypertrophy calculated as cardiomyocytes per square millimeter. Representative images in Additional file 1: Figure S7. n ≥ 6. c Lung weight normalized to each animal’s own tibia length. For all panels, two-way ANOVA results are displayed in Additional file 1: Table S3, and *p ≤ 0.05 according to Tukey’s multiple comparisons test

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