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Fig. 4 | Biology of Sex Differences

Fig. 4

From: The impact of biological sex on the response to noise and otoprotective therapies against acoustic injury in mice

Fig. 4

Differences in the slopes of ABR wave I amplitudes between male and female mice at 16 kHz. Growth of ABR wave I amplitude as a function of increasing stimuli levels at 16 kHz was compared by analysis of the slopes from linear regression of the data (dotted lines). The slopes are shown at baseline, 24 h, and 15 days post-noise exposure in males and females. a Slopes are reduced following noise exposure when compared to baseline for males (left) and females (right). Males partially recover at 15 days when compared to 24 h while females do not. b At baseline (left), the slope value from female wave I amplitude is higher than the value from males. The difference is maintained following noise exposure (right) at 24 h and 15 days. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001. Error bars indicate S.E.M. ns, non-significant

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