X chromosome dosage and presence of SRY shape sex-specific differences in DNA methylation at an autosomal region in human cells

Table 2 Multiple linear regression results between the first PC of methylation data and covariates

Covariate	Estimate	Std. error	t value	Pr(>\|t\|)
(Intercept)	− 19.44	13.63	− 1.426	0.167
Sex: male	25.90	12.78	2.027	0.054
Presence of SRY	− 3.542	16.81	− 0.211	0.835
Two or more X chromosomes	35.00	15.28	2.291	0.032
Interaction: SRY: two or more X chromosomes	− 51.38	22.41	− 2.293	0.031

ISSN: 2042-6410