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Fig. 2 | Biology of Sex Differences

Fig. 2

From: Effects of gut-derived endotoxin on anxiety-like and repetitive behaviors in male and female mice

Fig. 2

Effects of oral gavage of LPS on male WT and Tlr4−/− mice. Experiment 1: effects of oral gavage of LPS on open field test behavioral outcomes in male WT and Tlr4−/− mice. a LPS significantly decreased time in the center zone for male WT mice, but there was a slight trend toward increased time spent in the center zone for male Tlr4−/− mice. b Male Tlr4−/− mice had significantly increased average velocity, c time spent in stereotypic circling, and d number of stereotypic counts compared with male WT mice. e However, male WT mice had a significantly higher jump time compared to male Tlr4−/− mice. Error bars are 95% confidence intervals. *p < 0.05; #p = 0.107

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