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Table 5 Genes significantly upregulated in females (downregulated in males)

From: Sex differences in the late first trimester human placenta transcriptome

Gene symbol Chr Description Fold-change
(F/M)
FDRa FPKM in F FPKM in M
XIST X X inactive specific transcript (non-protein coding) 26.909 1.83E-172 21.68 0.06
KDM6A X Lysine demethylase 6A 1.674 1.36E-52 11.71 6.53
PUDP X Pseudouridine 5′-phosphatase 1.653 1.08E-21 12.47 7.04
EIF1AX-AS1 X EIF1AX antisense RNA 1 1.598 0.00204 2.84 1.34
MIR6895 X MicroRNA 6895 1.589 0.0353 2.25 0.63
ZNF300 5 Zinc finger protein 300 1.580 0.0257 1.44 0.60
RPL23AP11 14 Ribosomal protein L23a pseudogene 11 1.567 0.0302 2.40 1.27
Y_RNA 5 Y RNA 1.564 0.0438 7.13 3.63
MIR548B 6 MicroRNA 548b 1.552 0.0257 2.00 0.34
EIF1AX X Eukaryotic translation initiation factor 1A, X-linked 1.539 4.17E-10 20.05 11.57
RP13-216E22.4 X [No description] 1.538 0.000323 4.32 2.57
IQCJ-SCHIP1-AS1 3 IQCJ-SCHIP1 read through antisense RNA 1 1.518 0.0105 2.94 1.80
STS X Steroid sulfatase (microsomal), isozyme S 1.515 3.89E-05 93.88 57.49
RPS4X X Ribosomal protein S4, X-linked 1.490 8.09E-09 336.10 209.62
RP13-36G14.4 X [no description] 1.471 0.0481 1.64 1.10
DDX3X X DEAD-box helicase 3, X-linked 1.434 3.65E-18 74.41 47.42
ITGB8 7 Integrin subunit beta 8 1.402 0.0372 7.96 5.14
ZFX X Zinc finger protein, X-linked 1.392 1.81E-07 19.33 12.77
RAB30 11 RAB30, member RAS oncogene family 1.385 0.0494 2.18 1.37
JPX X JPX transcript, XIST activator (non-protein coding) 1.379 4.32E-08 5.40 3.62
KDM5C X Lysine demethylase 5C 1.364 0.00728 24.18 15.82
SMC1A X Structural maintenance of chromosomes 1A 1.360 0.000196 14.72 9.70
TRAPPC2 X Trafficking protein particle complex 2 1.358 0.000204 4.40 2.97
TBC1D32 6 TBC1 domain family member 32 1.349 0.00774 3.74 2.56
LINC00643 14 Long intergenic non-protein coding RNA 643 1.337 0.0416 6.02 4.01
RASSF6 4 Ras association domain family member 6 1.310 0.00516 12.23 8.74
LINC00630 X Long intergenic non-protein coding RNA 630 1.295 0.0112 2.92 2.13
BRCC3 X BRCA1/BRCA2-containing complex subunit 3 1.291 0.000701 10.84 7.50
CHM X CHM, Rab escort protein 1 1.269 0.0122 4.49 3.23
YIPF6 X Yip1 domain family member 6 1.267 0.0209 15.97 11.67
ZNF799 19 Zinc finger protein 799 1.261 0.0172 4.33 3.26
HDAC8 X Histone deacetylase 8 1.260 0.000121 3.96 2.92
PHTF1 1 Putative homeodomain transcription factor 1 1.234 0.0274 4.78 3.64
OFD1 X OFD1, centriole and centriolar satellite protein 1.230 0.00137 9.05 6.90
OSBPL3 7 Oxysterol binding protein-like 3 1.223 0.00921 4.80 3.73
  1. Sorted by fold-change. F = females. M = males
  2. aBenjamini-Hochberg false discovery rate
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