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Table 5 Genes significantly upregulated in females (downregulated in males)

From: Sex differences in the late first trimester human placenta transcriptome

Gene symbol

Chr

Description

Fold-change

(F/M)

FDRa

FPKM in F

FPKM in M

XIST

X

X inactive specific transcript (non-protein coding)

26.909

1.83E-172

21.68

0.06

KDM6A

X

Lysine demethylase 6A

1.674

1.36E-52

11.71

6.53

PUDP

X

Pseudouridine 5′-phosphatase

1.653

1.08E-21

12.47

7.04

EIF1AX-AS1

X

EIF1AX antisense RNA 1

1.598

0.00204

2.84

1.34

MIR6895

X

MicroRNA 6895

1.589

0.0353

2.25

0.63

ZNF300

5

Zinc finger protein 300

1.580

0.0257

1.44

0.60

RPL23AP11

14

Ribosomal protein L23a pseudogene 11

1.567

0.0302

2.40

1.27

Y_RNA

5

Y RNA

1.564

0.0438

7.13

3.63

MIR548B

6

MicroRNA 548b

1.552

0.0257

2.00

0.34

EIF1AX

X

Eukaryotic translation initiation factor 1A, X-linked

1.539

4.17E-10

20.05

11.57

RP13-216E22.4

X

[No description]

1.538

0.000323

4.32

2.57

IQCJ-SCHIP1-AS1

3

IQCJ-SCHIP1 read through antisense RNA 1

1.518

0.0105

2.94

1.80

STS

X

Steroid sulfatase (microsomal), isozyme S

1.515

3.89E-05

93.88

57.49

RPS4X

X

Ribosomal protein S4, X-linked

1.490

8.09E-09

336.10

209.62

RP13-36G14.4

X

[no description]

1.471

0.0481

1.64

1.10

DDX3X

X

DEAD-box helicase 3, X-linked

1.434

3.65E-18

74.41

47.42

ITGB8

7

Integrin subunit beta 8

1.402

0.0372

7.96

5.14

ZFX

X

Zinc finger protein, X-linked

1.392

1.81E-07

19.33

12.77

RAB30

11

RAB30, member RAS oncogene family

1.385

0.0494

2.18

1.37

JPX

X

JPX transcript, XIST activator (non-protein coding)

1.379

4.32E-08

5.40

3.62

KDM5C

X

Lysine demethylase 5C

1.364

0.00728

24.18

15.82

SMC1A

X

Structural maintenance of chromosomes 1A

1.360

0.000196

14.72

9.70

TRAPPC2

X

Trafficking protein particle complex 2

1.358

0.000204

4.40

2.97

TBC1D32

6

TBC1 domain family member 32

1.349

0.00774

3.74

2.56

LINC00643

14

Long intergenic non-protein coding RNA 643

1.337

0.0416

6.02

4.01

RASSF6

4

Ras association domain family member 6

1.310

0.00516

12.23

8.74

LINC00630

X

Long intergenic non-protein coding RNA 630

1.295

0.0112

2.92

2.13

BRCC3

X

BRCA1/BRCA2-containing complex subunit 3

1.291

0.000701

10.84

7.50

CHM

X

CHM, Rab escort protein 1

1.269

0.0122

4.49

3.23

YIPF6

X

Yip1 domain family member 6

1.267

0.0209

15.97

11.67

ZNF799

19

Zinc finger protein 799

1.261

0.0172

4.33

3.26

HDAC8

X

Histone deacetylase 8

1.260

0.000121

3.96

2.92

PHTF1

1

Putative homeodomain transcription factor 1

1.234

0.0274

4.78

3.64

OFD1

X

OFD1, centriole and centriolar satellite protein

1.230

0.00137

9.05

6.90

OSBPL3

7

Oxysterol binding protein-like 3

1.223

0.00921

4.80

3.73

  1. Sorted by fold-change. F = females. M = males
  2. aBenjamini-Hochberg false discovery rate
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Biology of Sex Differences

ISSN: 2042-6410

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