Significantly differentially expressed genes in placenta. a Chromosome and biotype distribution of the 58 DEGs, 35 upregulated in females (F) and 23 upregulated in males (M). “Auto” = autosomal chromosomes. b Ideogram of chromosome X showing the 25 significantly differentially expressed X-linked genes between first trimester male and female placentas (FDR < 0.05). Left: 3 genes upregulated in males. Right: 22 genes upregulated in females. The consensus calls for X inactivation status were adapted from Balaton et al.