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Table 1 Levels and statistical significance of the male SP-A2 AM miRNAs compared to SP-A KO in OxS and shown by IPA to be directly associated with genes IL-6, NF-kB, STAT3, BCL2, and FOXO1

From: SP-A2 contributes to miRNA-mediated sex differences in response to oxidative stress: pro-inflammatory, anti-apoptotic, and anti-oxidant pathways are involved

Mature ID

Fold regulation

p value

miR-191-5p

− 2.1515

0.00196

miR-153-3p

4.2526

0.000167

miR-15b-5p

− 1.7279

0.01395

miR-16-5p

− 1.8298

0.000532

miR-181a-5p

− 1.5004

0.000539

miR-183-5p

2.0782

0.000372

miR-195a-5p

− 1.2763

0.030639

miR-21a-5p

− 2.4629

0.009501

miR-9-5p

− 3.0084

0.001602

miR-486b-5p

1.407

0.196574

miR-1195

2.1028

0.000323

  1. − indicates downregulation