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Fig. 6 | Biology of Sex Differences

Fig. 6

From: SP-A2 contributes to miRNA-mediated sex differences in response to oxidative stress: pro-inflammatory, anti-apoptotic, and anti-oxidant pathways are involved

Fig. 6

Effect of O3 on IL-6, TNF-α, and IL-1β protein levels in the bronchoalveolar lavage of male SP-A2 and KO mice compared to FA exposure. a Protein levels were measured by ELISA 4 h post exposure. OxS significantly increased IL-6 levels in SP-A2 male mice compared to FA (control) SP-A2 mice (p < 0.05). b Protein levels were measured at 18 h post exposure in SP-A2 and KO. OxS significantly increased IL-6, IL-1β, and TNF-α in SP-A2 mice (p < 0.05) and significantly decreased in KO mice (p < 0.05). Data were generated using 3 animals/group, n = 18 and 3 replicate/animal

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