Regulatory and evolutionary signatures of sex-biased genes on both the X chromosome and the autosomes

Table 5 Mean nonsynonymous over synonymous rate (dN/dS), gene expression breadth, and how they vary according to sex bias of gene expression in Yoruba samples only

	dN/dS beta	dN/dS P value	Gene breadth beta	Gene breadth P value
Intercept	0.280676	< 2e−16*	45.8485	< 2e−16*
Male bias compared to unbiased	− 0.020105	0.962	− 19.6818	0.00179*
Female bias compared to unbiased	− 0.104992	0.608	0.7515	0.80780

All analyses were carried out using a univariate regression model with sex as a covariate. Betas denote coefficients in the univariate regression model, while P value denotes the P value of the coefficient
*Statistical significance at P value < 0.05 cutoff

ISSN: 2042-6410