Regulatory and evolutionary signatures of sex-biased genes on both the X chromosome and the autosomes

Table 4 Mean nonsynonymous over synonymous rate (dN/dS), gene expression breadth, and how they vary according to sex bias of gene expression in CEU samples only

	dNdS beta	dNdS P value	Gene breadth beta	Gene breadth P value
Intercept	0.2819	< 2e−16*	45.8583	< 2e−16*
Male bias compared to unbiased	− 0.087579	0.275	− 0.158	0.874
Female bias compared to unbiased	− 0.011096	0.883	− 0.9381	0.409

All analyses were carried out using a univariate regression model with sex as a covariate. Betas denote coefficients in the univariate regression model, while P value denotes the P value of the coefficient
*Statistical significance at P value < 0.05 cutoff

ISSN: 2042-6410