Regulatory and evolutionary signatures of sex-biased genes on both the X chromosome and the autosomes

Table 3 Mean nonsynonymous over synonymous rate (dN/dS), gene expression breadth, and how they vary according to sex bias of gene expression in LCLs containing both CEU and YRI population samples

	dN/dS beta	dN/dS P value	Gene breadth beta	Gene breadth P value
Intercept	0.2813	< 2e−16*	45.89	< 2e−16*
Male bias compared to unbiased	− 0.048	0.524	− 1.1670	0.3055
Female bias compared to unbiased	− 0.00394	0.956	− 2.3186	0.0332

All analyses were carried out using a univariate regression model with sex as a covariate. Betas denote coefficients in the univariate regression model, while P value denotes the P value of the coefficient
*Statistical significance at P value < 0.05 cutoff

ISSN: 2042-6410