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Table 3 Mean nonsynonymous over synonymous rate (dN/dS), gene expression breadth, and how they vary according to sex bias of gene expression in LCLs containing both CEU and YRI population samples

From: Regulatory and evolutionary signatures of sex-biased genes on both the X chromosome and the autosomes

  dN/dS beta dN/dS P value Gene breadth beta Gene breadth P value
Intercept 0.2813 < 2e−16* 45.89 < 2e−16*
Male bias compared to unbiased − 0.048 0.524 − 1.1670 0.3055
Female bias compared to unbiased − 0.00394 0.956 − 2.3186 0.0332
  1. All analyses were carried out using a univariate regression model with sex as a covariate. Betas denote coefficients in the univariate regression model, while P value denotes the P value of the coefficient
  2. *Statistical significance at P value < 0.05 cutoff