Fig. 3

Selection pressure dN/dS on escape genes as a measure of the covariates. Coefficients for linear regression of dN/dS, or the amount of selection pressure, as a function of the following variables. XY pair refers to whether the gene is part of an XY homologous pair, where the coefficient is the genes that are part of XY pairs compared to genes that are not. XAR or XCR refers to whether the gene belongs on the X added region on the X chromosome or the X conserved region strata, where the coefficient is for XCR compared to XAR. Escape status refers to whether the gene is classified as an escape gene, where the coefficient is for escape genes compared to non-escape genes. Average gene expression refers to the average level of gene expression among 264 female samples. Disease status refers to whether the gene was classified as a disease gene in OMIM