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Fig. 1 | Biology of Sex Differences

Fig. 1

From: Sex influences eQTL effects of SLE and Sjögren’s syndrome-associated genetic polymorphisms

Fig. 1

Chromosome and DNA strand location of SNPs with significant sex-influenced eQTL effect and surrounding genes in a ± 1 Mb interval. Genes with significantly different sex-influenced expression are labeled in red, and genes with non-sex influenced expression are labeled gray. a rs4637409, proxy SNP (r 2 = 1) for the SLE-associated rs10516487 (BANK1 locus) with a sex-dependent eQTL effect on SLC39A8 expression, located on chromosome 4, b rs10036748, proxy SNP (r 2 = 1) for the SLE-associated rs7708392 (TNIP1 locus) with a sex-dependent eQTL effect on CD74 expression, located on chromosome 5. c The SLE-associated rs6445975 (PXK locus), with a sex-dependent eQTL effect on PXK expression, located on chromosome 3. d rs922483 (proxy SNP for the pSS-associated rs2736345, r 2 = 1) and the SLE-associated rs13277113 (BLK/FAM167A locus) with sex-dependent eQTL effects on CTSB expression. e rs4938573, proxy SNP (r 2 = 0.865) for the pSS-associated rs7119038 (CXCR5 locus) with a sex-dependent eQTL effect on ARCN1 expression. f rs12753665, proxy SNP (r 2 = 0.821) for the SLE-associated rs10911363 (NCF2 locus) with a sex-dependent eQTL effect on DHX9 expression

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