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Table 1 Rating scale for evidence of sex/gender differences

From: Inclusion of sex and gender in biomedical research: survey of clinical research proposed at the University of Pennsylvania

Rating Definition
PubMed literature review of the topic under investigation revealed….
0 No evidence of sex or gender differences
1 Evidence of sex or gender differences, but studies are small, from only one lab, or not well controlled
2 Evidence of sex or gender  differences in at least one aspect of the topic under investigation. Studies may be small but come from multiple research groups or have been replicated.
3 Evidence of sex or gender  differences in at least two aspects of the topic under investigation. Studies may be small but come from multiple research groups or have been replicated.
4 Evidence of sex or gender differences in at least two aspects of the topic under investigation. Studies are large and from multiple groups.
NA No research has directly studied sex/gender differences for this disorder or condition.
  1. NA not available