Table 2 Frequency of extraglandular manifestations in female and male pSS patients in the exploratory cohort
From: Difference in clinical presentation between women and men in incident primary Sjögren’s syndrome
pSS all (n = 199) % (frequency) | Women (n = 186) % (frequency) | Men (n = 13) % (frequency) | p value | |
|---|---|---|---|---|
Presence of EGM | 30% (53/197) | 25% (47/185) | 46% (6/13) | 0.10 |
No. of EGM (mean ± SD) | 0.34 ± 0.64 | 0.30 ± 0.57 | 0.85 ± 1.21 | 0.05 |
No. of EGM in EGM+ patients (mean ± SD) | 1.26 ± 0.59 | 1.19 ± 0.45 | 1.83 ± 1.17 | 0.04 |
Extraglandular manifestationsa | ||||
Articular | ||||
Arthritis | 14% (28/197) | 14% (26/184) | 15% (2/13) | 1.00 |
Pulmonary | ||||
Interstitial lung disease | 1% (2/196) | 0% (0/183) | 15% (2/13) | 0.004 |
Alveolitis | 0.5% (1/197) | 0% (0/184) | 8% (1/13) | 0.07 |
Renal | ||||
Interstitial nephritis | 0.5% (1/197) | 0.5% (1/184) | 0% (0/13) | 1.00 |
Cutaneous | ||||
Cutaneous vasculitis | 4% (7/195) | 2% (4/182) | 23% (3/13) | 0.007 |
Neurological | ||||
Polyneuropathy | 4% (8/195) | 4% (7/182) | 8% (1/13) | 0.43 |
Mononeuritis | 0.5% (1/197) | 0.5% (1/184) | 0% (0/13) | 1.00 |
CNS involvement | 1% (2/197) | 1% (2/184) | 0% (0/13) | 1.00 |
Constitutional | ||||
Recurrent fever | 7% (14/197) | 7% (12/184) | 15% (2/13) | 0.23 |
Lymphadenopathy | ||||
Enlarged lymph nodes | 1% (4/197) | 2% (3/184) | 8% (1/13) | 0.24 |
Muscular | ||||
Myositis | 2% (3/197) | 0.5% (1/184) | 0% (0/13) | 1.00 |