Difference in clinical presentation between women and men in incident primary Sjögren’s syndrome

Table 1 Basic characteristics and objective pSS classification items of the patients in the exploratory cohort

	Women n = 186 % (frequency)	Men n = 13 % (frequency)	p value
Basic characteristics
Sex	93% (186/199)	7% (13/199)	<0.0001
Age at diagnosis, years (mean ± SD)	56 ± 14	46 ± 12	0.01
Item III. Ocular signs^a
Schirmer’s test (≤5 mm in 5 min)	70% (129/185)	77% (10/13)	0.58
Item IV. Histopathology^a
Minor salivary gland biopsy^a
Performed	85% (158/185)	92% (12/13)	0.49
Positive (focus score ≥1)	95% (149/157)	83% (10/12)	0.10
Item V. Salivary gland involvement^a
UWSF^b	78% (145/186)	77% (10/13)	0.93
Item VI. Autoantibodies^a
Positive (SSA and/or SSB)	55% (100/183)	54% (7/13)	0.96
SSA positive	53% (97/184)	46% (6/13)	0.65
SSB positive	30% (55/184)	33% (4/12)	0.80

^aAccording to the 2002 revised American–European Consensus Group criteria for Sjögren’s syndrome
^bUnstimulated whole salivary flow, ≤1.5 ml in 15 min
Bold values indicate statistically significant findings (p < 0.05)

ISSN: 2042-6410