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Table 2 Anterior-posterior model fit. Overall model chi-square (ChiSq) was always significant (P < 0.0001)

From: Sex differences in insular cortex gyri responses to a brief static handgrip challenge

Anterior vs. posterior   Gyrus, time
gyrus × time
Gyrus, time
Gyrus × time
Female left Female right
Model ChiSq (P < .0001) 424.31 472.4
−2 log-likelihood −3139.6 −2111.2
Effects (P) Gyrus *<0.0001 *<0.0001
Time *<0.0001 *<0.0001
Gyrus × time *<0.0001 *<0.0001
  Male left Male right
Model ChiSq (P < 0.0001) 1503.42 1086.15
−2 log-likelihood 367.1 −2072.2
Effects (P) Gyrus 0.12 *0.0024
Time *<0.0001 *<0.0001
Gyrus × time *<0.0001 *<0.0001
  1. The model fit is indicated by −2 × log-likelihood as calculated by SAS (higher indicates better fit). The P values for each variable are shown (italics and asterisk indicate P ≤ 0.05). Gyrus × time interaction was significant (P < 0.05) in all cases. (See also Additional files 3 and 4 for models with age and age interaction effects)