Table 5 Sex differences in ACE, ACE2, NEP, APN, and APA serum activities in younger (<55 years) and older (≥ 55 years) participants
From: Sex differences in the aging pattern of renin–angiotensin system serum peptidases
WOMEN | MEN | Mann–Whitney U | |||||||
|---|---|---|---|---|---|---|---|---|---|
Median | IQR | N | Median | IQR | N | Z | P value | ||
< 55 years | ACE | 820.3 | 249.77 | 28 | 841.4 | 281.02 | 31 | −0.728 | 0.467 |
ACE2 | 61.71 | 16.69 | 28 | 59.75 | 23.57 | 31 | −0.032 | 0.975 | |
NEP | 15474 | 1187.55 | 28 | 16203 | 2030.32 | 31 | −2.017 | 0.044 | |
APN | 9931 | 5046.74 | 28 | 11517 | 6916.75 | 31 | −1.653 | 0.098 | |
APA | 4304 | 1225.79 | 28 | 4281 | 1633.4 | 31 | −0.121 | 0.903 | |
> 55 years | ACE | 815.9 | 272.13 | 30 | 744.4 | 201.43 | 29 | −2.292 | 0.022 |
ACE2 | 71.11 | 16.22 | 30 | 70,05 | 30.92 | 29 | −0.378 | 0.706 | |
NEP | 15703 | 1812.15 | 30 | 15344 | 1668.93 | 29 | −0.562 | 0.574 | |
APN | 10238 | 6688.67 | 30 | 9973 | 4001.23 | 29 | −0.577 | 0.564 | |
APA | 4361 | 1240.15 | 30 | 3820 | 623.97 | 29 | −2.763 | 0.006 | |