Skip to main content

Advertisement

Table 2 Sex differences in liver histopathology

From: Sex and age differences in the expression of liver microRNAs during the life span of F344 rats

Lesion   52 weeks of age 78 weeks of age 104 weeks of age
  Female Male Female Male Female Male
Sex bias Incidence Avg. severity scoreb Incidence Avg. severity scoreb Incidence Avg. severity scoreb Incidence Avg. severity scoreb Incidence Avg. severity scoreb Incidence Avg. severity scoreb
Basophilic focusa Female 0/10 0/10 3/8 0/8 12/16 0/14
Hyperplasia, bile duct Male 0/10 8/10 1.6 2/8 1.5 7/8 1.4 2/16 2 10/14 1.9
Vacuolization, cytoplasm, hepatocyte Male 0/10 5/10 1.4 0/8 2/8 2.5 0/16 1/14 4
  1. aBasophilic loci scored as present or absent, without a severity score [53]
  2. bAverage among those animals showing the lesion