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Table 2 q values for the effect of DOX, sex, and the interaction between sex and DOX in regulating CYP genes expression based on a 2-way ANOVA analysis and a 5% false discovery rate

From: Sex-dependent alteration of cardiac cytochrome P450 gene expression by doxorubicin in C57Bl/6 mice

  1 day post-DOX 6 days post-DOX
DOX effect Sex effect Interaction effect DOX effect Sex effect Interaction effect
Cyp1a1 0.0001* 0.3346 0.3865 0.4935 0.0064* 0.1977
Cyp1b1 <0.0001* <0.0001* 0.0200* 0.0013* 0.0064* 0.0831
Cyp2c29 0.0012* 0.0006* 0.0200* 0.86 0.0433* 1.0000
Cyp2c44 0.0013* 0.051 0.1048 0.08 0.0064* 0.9700
Cyp2e1 <0.0001* 0.0164* 0.0364* 0.08 0.5371 1.0000
Cyp2j9 <0.0001* 0.2994 0.0567 0.2812 0.0727 1.0000
Cyp4a10 <0.0001* 0.0009* 0.3627 0.0943 0.1776 1.0000
  1. Specific post-hoc testing results can be found on the relevant figures
  2. *q < 0.05 denotes discoveries