Table 3 Summary of alterations in CRF-OE mice and WT littermates influenced by CRF-OE and fasting with sex difference
| Â | Basal | Fasting | |||
|---|---|---|---|---|---|
WT | CRF-OE | WT | CRF-OE | ||
Body weight | F < M | F↑ | ↓ F > M | ↓ < WT | |
Fat | F < M | ↑ | ↓ F < M | (−) | |
Adrenal glands | F > M | ↑ F > M | (−) | (−) | |
Fasting blood glucose |  |  | (−) | ↑ F > M | |
Refeeding |  |  | ↑ F > M | ↓ | |
Plasma | Corticosterone | (−) | ↑ | ↑ | (−) |
Leptin | F < M | ↑ | M↓ | (−) | |
Insulin | (−) | ↑ | ↓ | ↓ | |
Acyl ghrelin | (−) | ↓ | M↑ | (−) | |
PYY | (−) | (−) | M↓ | M↓ | |
Hypothalamus | NPY | (−) | F↑ | ↑ | (−) |
POMC | (−) | (−) | M↓ | M↓, F↑ | |
LepR | (−) | ↑ | (-) | (-) | |