|
Entire cohort
|
Men
|
Women
|
p for interaction
|
---|
n
|
HR
|
n
|
HR
|
n
|
HR
|
---|
Sex
|
Men
|
11,057
|
1.00
| | | | | |
Women
|
17,025
|
1.14 (0.81–1.60)
| | | | | |
p
| |
0.454
| | | | | |
Age
|
Years
|
28,079
|
1.06 (1.03–1.08)
|
11,054
|
1.02 (0.99–1.06)
|
17,022
|
1.07 (1.05–1.10)
|
0.045
|
p
| |
<0.001
| |
0.216
| |
<0.001
| |
Smoking
|
Never
|
10,642
|
1.00
|
3117
|
1.00
|
7525
|
1.00
| |
Former
|
9505
|
1.43 (0.94–2.17)
|
4781
|
1.58 (0.75–3.33)
|
4724
|
1.44 (0.86–2.42)
|
0.551
|
Occasionally
|
1261
|
2.74 (1.40–5.35)
|
532
|
2.00 (0.55–7.31)
|
729
|
3.29 (1.50–7.19)
|
0.367
|
Regularly
|
6674
|
2.87 (1.92–4.28)
|
2627
|
3.57 (1.70–7.47)
|
4047
|
2.62 (1.61–4.27)
|
0.397
|
p trend
| |
<0.001
| |
<0.001
| |
<0.001
| |
Environmental tobacco smoke at work
|
Never
|
12,222
|
1.00
|
3759
|
1.00
|
8463
|
1.00
| |
For <10 years
|
3296
|
1.49 (0.89–2.49)
|
1092
|
1.95 (0.82–4.66)
|
2204
|
1.29 (0.68–2.47)
|
0.450
|
For 10–20 years
|
3370
|
1.30 (0.78–2.17)
|
1259
|
1.53 (0.64–3.66)
|
2111
|
1.17 (0.61–2.24)
|
0.607
|
For >20 years
|
6258
|
1.73 (1.15–2.58)
|
3744
|
1.45 (0.74–2.84)
|
2514
|
2.01 (1.21–3.31)
|
0.259
|
p trend
| |
0.011
| |
0.359
| |
0.013
| |
Alcohol
|
g/day
|
28,079
|
1.00 (0.99–1.01)
|
11,054
|
1.00 (0.98–1.01)
|
17,022
|
1.01 (0.99–1.03)
|
0.469
|
p
| |
0.999
| |
0.528
| |
0.444
| |
Diabetes >24 months prior pancreatic cancer or endpoint
|
No
|
23,537
|
1.00
|
8768
|
1.00
|
14,769
|
1.00
| |
Yes
|
4545
|
0.88 (0.57–1.34)
|
2289
|
1.07 (0.59–1.95)
|
2256
|
0.72 (0.38–1.34)
|
0.358
|
p
| |
0.545
| |
0.819
| |
0.300
| |
- Adjusted for sex, age, smoking, alcohol consumption, and diabetes