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Table 3 Risk of incident pancreatic cancer in relation with sex, age, smoking, alcohol consumption, and prevalent diabetes

From: Pancreatic cancer risk in relation to sex, lifestyle factors, and pre-diagnostic anthropometry in the Malmö Diet and Cancer Study

  Entire cohort Men Women p for interaction
n HR n HR n HR
Sex
 Men 11,057 1.00      
 Women 17,025 1.14 (0.81–1.60)      
p   0.454      
Age
 Years 28,079 1.06 (1.03–1.08) 11,054 1.02 (0.99–1.06) 17,022 1.07 (1.05–1.10) 0.045
p   <0.001   0.216   <0.001  
Smoking
 Never 10,642 1.00 3117 1.00 7525 1.00  
 Former 9505 1.43 (0.94–2.17) 4781 1.58 (0.75–3.33) 4724 1.44 (0.86–2.42) 0.551
 Occasionally 1261 2.74 (1.40–5.35) 532 2.00 (0.55–7.31) 729 3.29 (1.50–7.19) 0.367
 Regularly 6674 2.87 (1.92–4.28) 2627 3.57 (1.70–7.47) 4047 2.62 (1.61–4.27) 0.397
p trend   <0.001   <0.001   <0.001  
Environmental tobacco smoke at work
 Never 12,222 1.00 3759 1.00 8463 1.00  
 For <10 years 3296 1.49 (0.89–2.49) 1092 1.95 (0.82–4.66) 2204 1.29 (0.68–2.47) 0.450
 For 10–20 years 3370 1.30 (0.78–2.17) 1259 1.53 (0.64–3.66) 2111 1.17 (0.61–2.24) 0.607
 For >20 years 6258 1.73 (1.15–2.58) 3744 1.45 (0.74–2.84) 2514 2.01 (1.21–3.31) 0.259
p trend   0.011   0.359   0.013  
Alcohol
 g/day 28,079 1.00 (0.99–1.01) 11,054 1.00 (0.98–1.01) 17,022 1.01 (0.99–1.03) 0.469
p   0.999   0.528   0.444  
Diabetes >24 months prior pancreatic cancer or endpoint
 No 23,537 1.00 8768 1.00 14,769 1.00  
 Yes 4545 0.88 (0.57–1.34) 2289 1.07 (0.59–1.95) 2256 0.72 (0.38–1.34) 0.358
p   0.545   0.819   0.300  
  1. Adjusted for sex, age, smoking, alcohol consumption, and diabetes