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Table 3 Risk of incident pancreatic cancer in relation with sex, age, smoking, alcohol consumption, and prevalent diabetes

From: Pancreatic cancer risk in relation to sex, lifestyle factors, and pre-diagnostic anthropometry in the Malmö Diet and Cancer Study

 

Entire cohort

Men

Women

p for interaction

n

HR

n

HR

n

HR

Sex

 Men

11,057

1.00

     

 Women

17,025

1.14 (0.81–1.60)

     

p

 

0.454

     

Age

 Years

28,079

1.06 (1.03–1.08)

11,054

1.02 (0.99–1.06)

17,022

1.07 (1.05–1.10)

0.045

p

 

<0.001

 

0.216

 

<0.001

 

Smoking

 Never

10,642

1.00

3117

1.00

7525

1.00

 

 Former

9505

1.43 (0.94–2.17)

4781

1.58 (0.75–3.33)

4724

1.44 (0.86–2.42)

0.551

 Occasionally

1261

2.74 (1.40–5.35)

532

2.00 (0.55–7.31)

729

3.29 (1.50–7.19)

0.367

 Regularly

6674

2.87 (1.92–4.28)

2627

3.57 (1.70–7.47)

4047

2.62 (1.61–4.27)

0.397

p trend

 

<0.001

 

<0.001

 

<0.001

 

Environmental tobacco smoke at work

 Never

12,222

1.00

3759

1.00

8463

1.00

 

 For <10 years

3296

1.49 (0.89–2.49)

1092

1.95 (0.82–4.66)

2204

1.29 (0.68–2.47)

0.450

 For 10–20 years

3370

1.30 (0.78–2.17)

1259

1.53 (0.64–3.66)

2111

1.17 (0.61–2.24)

0.607

 For >20 years

6258

1.73 (1.15–2.58)

3744

1.45 (0.74–2.84)

2514

2.01 (1.21–3.31)

0.259

p trend

 

0.011

 

0.359

 

0.013

 

Alcohol

 g/day

28,079

1.00 (0.99–1.01)

11,054

1.00 (0.98–1.01)

17,022

1.01 (0.99–1.03)

0.469

p

 

0.999

 

0.528

 

0.444

 

Diabetes >24 months prior pancreatic cancer or endpoint

 No

23,537

1.00

8768

1.00

14,769

1.00

 

 Yes

4545

0.88 (0.57–1.34)

2289

1.07 (0.59–1.95)

2256

0.72 (0.38–1.34)

0.358

p

 

0.545

 

0.819

 

0.300

 
  1. Adjusted for sex, age, smoking, alcohol consumption, and diabetes