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Table 2 Risk of incident pancreatic cancer in relation with sex, age, smoking, alcohol consumption, and prevalent diabetes

From: Pancreatic cancer risk in relation to sex, lifestyle factors, and pre-diagnostic anthropometry in the Malmö Diet and Cancer Study

 

Entire cohort

Men

Women

p for interaction

n

HR

n

HR

n

HR

 

Sex

 Men

11,063

1.00

     

 Women

17,031

1.08 (0.79–1.48)

     

p

 

0.636

     

Age

 Years

28,094

1.05 (1.02–1.07)

11,063

1.02 (0.98–1.06)

17,031

1.06 (1.03–1.09)

0.069

p

 

<0.001

 

0.362

 

<0.001

 

Smoking

 Never

10,642

1.00

3117

1.00

7525

1.00

 

 Former

9505

1.43 (0.94–2.16)

4781

1.55 (0.74–3.26)

4724

1.46 (0.87–2.45)

0.545

 Occasionally

1261

2.74 (1.40–5.34)

532

1.96 (0.54–7.13)

729

3.35 (1.54–7.31)

0.368

 Regularly

6674

2.86 (1.92–4.27)

2627

3.49 (1.67–7.29)

4047

2.66 (1.64–4.32)

0.393

p trend

 

<0.001

 

<0.001

 

<0.001

 

Environmental tobacco smoke at work

 Never

12,225

1.00

3760

1.00

8465

1.00

 

 For <10 years

3297

1.44 (0.86–2.41)

1093

1.99 (0.83–4.74)

2204

1.23 (0.64–2.34)

0.429

 For 10–20 years

3371

1.40 (0.84–2.34)

1259

1.71 (0.72–4.07)

2112

1.25 (0.65–2.34)

0.703

 For >20 years

6259

2.03 (1.37–3.02)

3745

1.86 (0.97–3.58)

2514

2.30 (1.40–3.77)

0.256

p trend

 

0.001

 

0.082

 

0.002

 

Alcohol

 g/day

28,094

1.00 (0.99–1.02)

11,063

1.00 (0.98–1.01)

17,031

1.01 (0.99–1.04)

0.352

p

 

0.638

 

0.737

 

0.206

 

Diabetes >24 months prior pancreatic cancer or endpoint

 No

23,547

1.00

8773

1.00

14,774

1.00

 

 Yes

4547

0.86 (0.58–1.36)

2290

1.09 (0.60–1.98)

2257

0.72 (0.38–1.34)

0.366

p

 

0.576

 

0.784

 

0.299

 
  1. Adjusted for age and sex