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Table 2 Echocardiographic and cardiovascular magnetic resonance data of male and female patients with hypertrophic cardiomyopathy

From: Sex-related differences in the associations between plasma free fatty acid levels and clinical features in patients with hypertrophic cardiomyopathy

Variable Male (n = 243) Female (n = 169) p value
Echocardiography
 Systolic anterior motion, n (%) 215 (88.5%) 156 (92.3%) 0.242
 LVOT obstruction, n (%) 241 (99.2%) 168 (99.4%) 1.000
 Severe mitral regurgitation, n (%) 13 (5.3%) 11 (6.5%) 0.672
 LVOTG at rest (mmHg) 64.3 ± 35.4 79.6 ± 35.9 <0.001
 LVOTG after provocation (mmHg)a 82.1 ± 31.4 66.3 ± 28.7 0.031
Cardiovascular magnetic resonance
 Left atrium diameter (mm) 42.1 ± 8.1 42.8 ± 8.1 0.362
 LV end-diastolic diameter (mm) 46.8 ± 5.0 45.0 ± 5.2 <0.001
 Maximum wall thickness (mm) 25.3 ± 5.5 23.4 ± 4.9 <0.001
 LV ejection fraction (%) 67.8 ± 8.0 69.1 ± 7.6 0.097
 LV end-diastolic volume (mL) 135.0 ± 34.4 114.3 ± 27.1 <0.001
 LV end-systolic volume (mL) 44.7 ± 18.9 36.4 ± 15.4 <0.001
 Stroke volume (mL) 91.1 ± 23.6 78.4 ± 17.6 <0.001
 Cardiac output (L/min) 6.3 ± 1.8 5.3 ± 1.3 <0.001
 LV mass (g) 181.3 ± 73.7 128.6 ± 54.2 <0.001
 LV end-diastolic volume index (mL/m2) 72.5 ± 16.4 70.1 ± 15.2 0.140
 LV end-systolic volume index (mL/m2) 23.7 ± 9.3 22.0 ± 8.7 0.075
 Stroke volume index (mL/m2) 48.9 ± 11.3 48.1 ± 9.9 0.502
 Cardiac index (L/min/m2) 3.4 ± 0.9 3.3 ± 0.8 0.306
 LV mass index (g/m2) 96.8 ± 37.6 78.6 ± 31.5 <0.001
  1. Data are expressed as mean ± SD or number (percentage)
  2. HCM hypertrophic cardiomyopathy, LV left ventricular, LVOTG left ventricular outflow tract gradient
  3. aProvoked LVOTG data were available in 96 patients