Skip to main content

Advertisement

Table 2 Main effect of loci that control eosinophil numbers in the inguinal lymph nodes of L. major-infected F2 hybrids between CcS-9 and BALB/c

From: Gene-specific sex effects on eosinophil infiltration in leishmaniasis

Locus Group Marker Genotype P value Corr. P value % of expl. var.
CC CS SS
Lmr14 Both sexes D2Mit283 2.62 1.229 ±0.003 3.62 1.234 ±0.002 2.67 1.229 ±0.002 NS NS NA
     (n = 57)   (n = 111)   (n = 74)    
Females 1.24 1.217 ±0.003 1.45 1.220 ±0.002 1.62 1.221 ±0.003 NS NS NA
   (n = 35)   (n = 61)   (n = 32)    
Males both crosses 5.15 1.239 ±0.005 8.94 1.247 ±0.003 4.02 1.236 ±0.004 5.5 × 10−2 NS NA
   (n = 22)   (n = 50)   (n = 41)    
Males (BALB/c × CcS-9)F2 3.37 1.233 ±0.006 9.09 1.242 ±0.004 3.78 1.235 ±0.005 NS NS NA
   (n = 15)   (n = 32)   (n = 27)     
Males (CcS-9 × BALB/c)F2 13.63 1.253 ±0.005 18.34 1.257 ±0.004 4.51 1.237 ±0.005 1.08 × 10−4 8.11 × 10 −3 36.22
   (n = 7)   (n = 18)   (n = 14)    
Lmr25 Both sexes D5Mit143 2.07 1.225 ±0.003 4.33 1.237 ±0.002 1.96 1.225 ±0.003 9.53 × 10−4 4.36 × 10 −2 5.02
     (n = 66)   (n = 107)   (n = 67)    
Females 1.09 1.215 ±0.003 2.04 1.225 ±0.002 1.20 1.216 ±0.003 6.3 × 10−3 NS NA
   (n = 37)   (n = 56)   (n = 36)    
Males 5.71 1.241 ±0.004 7.40 1.244 ±0.003 4.41 1.237 ±0.004 NS NS NA
   (n = 31)   (n = 51)   (n = 31)    
  1. Mean and SE values were obtained by analysis of variance. In order to obtain normal distribution required for analysis of variance, the value of eosinophil numbers in the inguinal lymph nodes was transformed by using the 0.1th power of natural logarithm of the (observed value ×1000). The numbers in bold give the average non-transformed values. C and S indicate the presence of BALB/c and STS allele, respectively
  2. n number of mice