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Fig. 3 | Biology of Sex Differences

Fig. 3

From: Comparisons of chromosome Y-substituted mouse strains reveal that the male-specific chromosome modulates the effects of androgens on cardiac functions

Fig. 3

Effects of either surgery (ac) or of chronic treatment with DHT (df) on expression levels of Pln, Ttn, and Fhl2 in hearts from C57BL/6J and C57.YA/J male mice. Values at each time-point correspond to mean ± SD (n = 6–8). P values correspond to those for the interaction of strain with the effect of surgery. The asterisks (ad) correspond to the significance of the differences detected by post-hoc Tukey multiple comparison tests (*P < 0.05; **P < 0.01; ***P < 0.001). e, f Significance of differences as detected by t tests between animals implanted with either empty (VEH) or DHT-filled (DHT) silastic tubes (*P < 0.05; ***P < 0.001)

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