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Table 1 Demographic data for the cohorts used for population volume kinetic analysis

From: The elimination half-life of crystalloid fluid is shorter in female than in male volunteers: a retrospective population kinetic analysis

Study no. Females/males Infusions Age (years) Body weight (kg) Fluid volume (ml/kg) Infusion time (min) Infusion rate (ml/min/kg) Study length (min) Reference no.
1 0/10 10 22 (18–28) 79 (65–101) 20 30 0.666 180 [9]
2 10/0 10 29 (21–39) 63 (58–67) 25 30 0.833 240 [10]
3 0/10 10 32 (24–44) 81 (72–95) 25 30 0.833 240 [11]
4 0/10 19a 22 (19–37) 80 (75–100) 5, 10 15 0.333, 0.666 120 [12]
5 0/10 19a 31 (28–40) 82 (70–97) 25 15, 30 0.83, 1.66 90 [13]
6 8/0 31b 32 (23–46) 61 (52–75) 15, 25 15, 30, 45, 80 0.31, 0.42, 0.55, 0.83, 1.66 135, 150, 165, 310 [14]
7 0/12 12 30 (20–38) 84 (71–98) 25 30 0.833 240 None
  1. Data are the mean (range)
  2. aEach male underwent two infusions with different volume or rate. One experiment in one male was excluded due to missed urinary excretion
  3. bSix volunteers underwent three to six infusions and two received one infusion each