Skip to main content

Table 3 Guidelines for conducting rigorous subgroup analysis by sex and gender in randomized controlled trials

From: How to study the impact of sex and gender in medical research: a review of resources

1

State the subgroup analysis a priori

2

Provide a rationale for performing the subgroup analysis

3

Offer a hypothesis regarding the outcome of the subgroup analysis

4

Adjust p values for the number of comparisons being made

5

Emphasize overall findings instead of subgroup analysis findings because results can only be considered hypothesis generating

  1. Adapted from “Sex and Gender Subgroup Analyses of Randomized Trials”