Skip to main content

Advertisement

Table 3 Visceral sensitivity in adult female animals following ELS across the estrus cycle

From: Sex-related differences in pain behaviors following three early life stress paradigms

Phase Treatment 0 mmHg 20 mmHg 40 mmHg 60 mmHg
Metestrus/diestrus Control 1.1 ± 0.3 5.1 ± 1.6 16.4 ± 3.1 27.3 ± 3.3
  Maternal separation 4.3 ± 1.4 8.3 ± 1.6 17.0 ± 2.4 28.8 ± 1.2
  Control 0.6 ± 0.2 2.9 ± 0.8 13.3 ± 0.7 23.6 ± 1.9
  Limited nesting 0.5 ± 0.3 3.5 ± 1.3 15.8 ± 0.9 23.3 ± 1.4
  Odor only 0.2 ± 0.2 2.5 ± 0.8 12.2 ± 1.5 21.2 ± 1.5
  Predictable 1.1 ± 0.3 4.7 ± 0.6 12.1 ± 1.3 19.4 ± 0.9
  Unpredictable 0.5 ± 0.3 5.3 ± 1.3 14.8 ± 3.3* 27.0 ± 3.7*
Proestrus/estrus Control 3.6 ± 2.1 8.0 ± 3.0 20.8 ± 4.1 34.6 ± 4.9
  Maternal separation 3.3 ± 0.9 7.1 ± 0.9 19.6 ± 2.1 30.9 ± 3.1
  Control 0.6 ± 0.6 3.0 ± 1.3 17.4 ± 0.6*** 26.6 ± 1.3**
  Limited nesting 0.9 ± 0.5 1.8 ± 0.4 18.9 ± 0.9 26.4 ± 2.4
  Odor only 0.5 ± 0.3 3.5 ± 1.0 13.8 ± 6.3 27.3 ± 1.3
  Predictable 3.8 ± 2.2 5.5 ± 0.3 23.0 ± 3.3*** 27.0 ± 1.7***
  Unpredictable 1.0 ± 0.4 5.2 ± 1.0 22.0 ± 0.9 32.5 ± 2.6*
  1. Mean ± SEM
  2. *p < 0.05 vs same cycle control, **p < 0.05 metestrus/diestrus vs proestrus/estrus within same group