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Table 2 Somatic sensitivity in adult female animals following ELS across the estrus cycle

From: Sex-related differences in pain behaviors following three early life stress paradigms

Phase Treatment Gram force (g) to elicit withdrawal
Metestrus/diestrus Control 56.2 ± 4.2
  Maternal separation 50.7 ± 6.3
  Control 60.2 ± 1.4
  Limited nesting 59.2 ± 0.8
  Odor only 51.5 ± 2.7
  Predictable 53.2 ± 2.0
  Unpredictable 49.8 ± 5.3
Proestrus/estrus Control 81.8 ± 4.1***
  Maternal separation 74.2 ± 1.8***
  Control 70.7 ± 2.8**
  Limited nesting 66.7 ± 1.7**
  Odor only 66.3 ± 0.9**
  Predictable 65.8 ± 1.4***
  Unpredictable 71.3 ± 2.8**
  1. Mean ± SEM
  2. **p < 0.05 vs same cycle control
  3. ***p < 0.05 metestrus/diestrus vs proestrus/estrus within same group