Skip to main content

Advertisement

Table 3 Summary of nonsynonymous substitutions (NSs) across callitrichine primates in genes relevant for sexual differentiation

From: Gene changes may minimize masculinizing and defeminizing influences of exposure to male cotwins in female callitrichine primates

Gene # NSsa All callitrichines Callithrix specific Variable callitrichine Callimico reversion % Altered proteinb % Radical AAc
AMH 14 8 1 5 0 21.4 64.3
AMHR2 11 1 7 3 1 18.2 80.0
AR 10 6 3 1 0 0 80.0
CYP19A1 6 3 0 2 1 0 83.3
SHBG 4 2 1 0 0 0 100
SRD5A2 8 6 0 2 0 12.5 75.0
  1. All callitrichines NSs common to all callitrichines sampled, Callithrix specific NSs documented only in Callithrix, Variable callitrichine NSs identified in some, but not all callitrichines, Callimico reversion NSs in single-offspring Callimico that represent a reversion to Saimiri residue
  2. aTotal #NSs identified in callitrichines
  3. bNSs that represent significantly altered protein structure/function by PROVEAN
  4. cNSs that lead to at least one physicochemical change in amino acid residue