Skip to main content

Advertisement

Table 1 Patient demographics and clinical history

From: Characterization of osteoarthritic human knees indicates potential sex differences

Variable Female Male p valuea
Median age (IQR) - years 70 (68, 71) 69 (66, 72) 0.42
Median body mass index (IQR) - kg/m2 26.2 (25.6, 28.1) 27.0 (24.3, 28.6) 0.34
Vitamin D use - no. (%)b    0.14
 Currently 6 (60 %) 3 (30 %)  
 Previously 3 (30 %) 2 (20 %)  
 Never 1 (10 %) 5 (50 %)  
Median 25-hydroxy D3 (IQR) - ng/ml 42.1 (33.7, 47.2) 38.4 (31.0, 52.6) 0.79
Bisphosphonates use - no. (%)b    0.47
 Previously 2 (20 %) 0 (0 %)  
 Never 8 (80 %) 10 (100 %)  
Estrogen use - no. (%)b    <0.001
 Currently 4 (40 %) 0 (0 %)  
 Previously 4 (40 %) 0 (0 %)  
 Never 2 (20 %) 10 (100 %)  
Previously injured a knee so badly it was difficult to walk for at least a week - no. (%) 0 (0 %) 3 (30 %) 0.21
Prior knee surgery - no. (%) 6 (60 %) 6 (60 %) 1.00
Prior intra-articular injections of steroids - no. (%) 7 (70 %) 5 (50 %) 0.65
Median no. of steroid injections (IQR) 1 (0, 1)c 1 (0, 3) 0.58
Prior intra-articular injection of hyaluronic acid - no. (%) 3 (30 %) 5 (50 %) 0.65
Median no. of hyaluronic injections (IQR) 0 (0, 1) 2 (0, 3) 0.30
Knee to be replaced - no. (%)    1.00
 Right 6 (60 %) 6 (60 %)  
 Left 4 (40 %) 4 (40 %)  
  1. IQR interquartile range
  2. a p values result from a Wilcoxon rank sum test for numerical variables and Fisher’s exact test for categorical variables
  3. b p values are based on categorization as currently or previously used vs. never used
  4. cInformation was not available for 1 patient