Skip to main content

Table 2 Echocardiograph measurements

From: Sexual dimorphism in myocardial acylcarnitine and triglyceride metabolism

  Male Female ANOVA
Parameter Wistar GK Wistar GK Phenotype Sex Phenotype × sex
HR (bpm) 396.22 ± 16.90 345.56 ± 27.34* 388.13 ± 16.36 324.67 ± 25.41‡ <0.001 0.343 0.67
LVPWId (μm/g) 0.0037 ± 0.0003 0.0049 ± 0.0005 0.0046 ± 0.0003 0.0063 ± 0.0002 <0.0005 <0.0005 0.31
LVPWIs (μm/g) 0.0060 ± 0.0003 0.0073 ± 0.0006† 0.0083 ± 0.0005 0.0102 ± 0.0008 <0.0005 <0.0005 0.49
LVIDId (μm/g) 0.0150 ± 0.001 0.0219 ± 0.001 0.0240 ± 0.001 0.0291 ± 0.001‡ <0.0005 <0.0005 0.35
LVIDIs (μm/g) 0.0087 ± 0.0007 0.0136 ± 0.0013 0.0120 ± 0.0013 0.0170 ± 0.0009 <0.0005 <0.0005 0.82
LVMI (mg/g) 2.45 ± 0.15 2.84 ± 0.18* 2.52 ± 0.10 3.04 ± 0.19* <0.0005 0.23 0.54
FS (%) 43.45 ± 1.78 38.20 ± 4.44 48.52 ± 3.91 41.57 ± 3.45 <0.05 0.092 0.728
E (mm/s) 1041.33 ± 82.04 818.50 ± 39.05* 838.67 ± 49.27 750.57 ± 48.21* <0.01 <0.01 0.161
E′ (mm/s) 54.43 ± 8.10 36.26 ± 6.77* 44.65 ± 3.23 30.04 ± 5.51‡ <0.01 0.124 0.725
A (mm/s) 813.67 ± 76.65 560.50 ± 38.94* 727.50 ± 57.27 535.43 ± 48.99‡ <0.0005 0.257 0.528
A′ (mm/s) 51.35 ± 6.4 52.27 ± 5.97 62.67 ± 5.71 55.24 ± 6.07 0.527 0.173 0.419
  1. Values are mean ± SEM. Italicized values indicate significance at P < 0.05. *P < 0.05, ‡P < 0.01, †P < 0.001 GK significantly different than Wistars
  2. GK Goto-Kakizaki rats, HR heart rate, LVPWId and LVPWIs left ventricle posterior wall index during diastole and systole, respectively, LVIDId and LVIDIs left ventricle internal dimension index during diastole and systole, respectively, LVMI Left ventricle mass index as measure of cardiac structural parameters, FS fractional shortening, E, E′, A, A′ measures of transmitral velocity