Fig. 2

Sex differences in NEFA homeostasis. a Profile of NEFA in cardiac tissue, as measured by LC-MS/MS, presented as fold change between NOD and Wistar rats by sex. An asterisk (*) indicates that the fold change is statistically significant. A section sign (§) indicates that the ANOVA interaction term is significant, and therefore, the fold changes in males and females also are. A dagger (†) indicates that in the ANOVA model, the overall sex difference is statistically significant. b Distribution of enriched and depleted of NEFA moities. The asterisk (*) indicates that the distribution is significantly different than a binomial distribution with mean = 0.5. The dagger (†) indicates that the distribution in males and females differ significantly. c, d The distribution of FAs based on their chain-length and degree of saturation, respectively. Data is presented as mean ± SEM (N = 6). An asterisk (*) indicates that the difference in adjacent bars is statistically significant. A section sign (§) indicates that the ANOVA interaction term is significant. P < 0.05 is the significance level for all tests