Table 2 Androgen-regulated miRNAs and their corresponding mRNA target(s) on GD 18.0 classified according to several biological processes
From: Expression profile of androgen-modulated microRNAs in the fetal murine lung
| Biological process | Gestational day 18.0 | |
|---|---|---|
| miRNA | mRNA target | |
| Lipid metabolic process | mmu-miR-30e | B3gnt5; St8sia4; Nr5a2; Myo5a |
| mmu-miR-146b | Myo5a | |
| mmu-miR-361-3p | Smg1 | |
| Developmental programmed cell death | mmu-miR-30e | Bcl2 |
| mmu-miR-202-5p | Bcl2 | |
| mmu-miR-3058 | Bcl2 | |
| mmu-miR-669h-3p | Bcl2 | |
| mmu-miR-703 | Bcl2 | |
| Cell proliferation | mmu-miR-130a | Appl1; Zeb2 |
| mmu-miR-146b | Appl1 | |
| mmu-miR-452-3p | Appl1 | |
| mmu-miR-202-5p | Bcl2 | |
| mmu-miR-3058 | Bcl2 | |
| mmu-miR-703 | Bcl2 | |
| mmu-miR-3473d | Bcl2l2 | |
| mmu-miR-669h-3p | Hdgfrp3; Bcl2 | |
| mmu-miR-1251 | Igf1 | |
| mmu-miR-344f-3p | Igf1 | |
| mmu-miR-709 | Myc; Igf1 | |
| mmu-miR-466l-5p | Igf1 | |
| mmu-miR-30e | Igf1; Bcl2; Zeb2 | |
| Androgen receptor signaling pathway | mmu-miR-146b | Med13 |
| mmu-miR-3473d | Med13 | |
| mmu-miR-669h-3p | Med13 | |
| mmu-miR-703 | Med13 | |
| mmu-miR-883a-3p | Med13 | |
| Lung cell differentiation | mmu-miR-1251 | Igf1 |
| mmu-miR-30e | Igf1 | |
| mmu-miR-344f-3p | Igf1; Creb1 | |
| mmu-miR-466l-5p | Creb1; Igf1 | |
| mmu-miR-709 | Igf1 | |
| mmu-miR-130a | Creb1 | |
| mmu-miR-202-5p | Creb1 | |
| mmu-miR-703 | Creb1 | |
| Cell-cell signaling | mmu-miR-883a-3p | Gls |
| mmu-miR-130a | Lrp6 | |
| mmu-miR-709 | Lrp6 | |
| mmu-miR-30e | Myo5a; Lrp6 | |
| mmu-miR-146b | Myo5a | |
| Lung development | mmu-miR-344f-3p | Igf1; Creb1 |
| mmu-miR-466l-5p | Igf1 | |
| mmu-miR-202-5p | Creb1 | |
| mmu-miR-703 | Creb1 | |
| mmu-miR-130a | Creb1 | |
| mmu-miR-1251 | Foxp2; Igf1 | |
| mmu-miR-3058 | Igf1; Foxp2 | |
| mmu-miR-490-5p | Foxp2; Igf1 | |
| mmu-miR-709 | Foxp2; Igf1 | |
| mmu-miR-669h-3p | Foxp2; Igf1 | |
| mmu-miR-30e | Igf1 | |
| Wnt signaling pathway | mmu-miR-669h-3p | Apc |
| mmu-miR-130a | Lrp6 | |
| mmu-miR-30e | Lrp6 | |
| mmu-miR-709 | Myc; Lrp6 | |
| mmu-miR-105 | Usp34 | |
| mmu-miR-669b-3p | Mitf | |
| Steroid metabolic process | mmu-miR-30e | Nr5a2 |
| Angiogenesis | mmu-miR-30e | Pdcd10 |
| mmu-miR-202-5p | Naa15 | |
| mmu-miR-3085-5p | Naa15 | |
| mmu-miR-883a-3p | Naa15 | |
| mmu-miR-669h-3p | Srpk2 | |
| Transforming growth factor beta receptor signaling pathway | mmu-miR-130a | Creb1 |
| mmu-miR-202-5p | Creb1 | |
| mmu-miR-344f-3p | Creb1 | |
| mmu-miR-703 | Creb1 | |
