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Table 2 Androgen-regulated miRNAs and their corresponding mRNA target(s) on GD 18.0 classified according to several biological processes

From: Expression profile of androgen-modulated microRNAs in the fetal murine lung

Biological process Gestational day 18.0
miRNA mRNA target
Lipid metabolic process mmu-miR-30e B3gnt5; St8sia4; Nr5a2; Myo5a
  mmu-miR-146b Myo5a
  mmu-miR-361-3p Smg1
Developmental programmed cell death mmu-miR-30e Bcl2
  mmu-miR-202-5p Bcl2
  mmu-miR-3058 Bcl2
  mmu-miR-669h-3p Bcl2
  mmu-miR-703 Bcl2
Cell proliferation mmu-miR-130a Appl1; Zeb2
  mmu-miR-146b Appl1
  mmu-miR-452-3p Appl1
  mmu-miR-202-5p Bcl2
  mmu-miR-3058 Bcl2
  mmu-miR-703 Bcl2
  mmu-miR-3473d Bcl2l2
  mmu-miR-669h-3p Hdgfrp3; Bcl2
  mmu-miR-1251 Igf1
  mmu-miR-344f-3p Igf1
  mmu-miR-709 Myc; Igf1
  mmu-miR-466l-5p Igf1
  mmu-miR-30e Igf1; Bcl2; Zeb2
Androgen receptor signaling pathway mmu-miR-146b Med13
  mmu-miR-3473d Med13
  mmu-miR-669h-3p Med13
  mmu-miR-703 Med13
  mmu-miR-883a-3p Med13
Lung cell differentiation mmu-miR-1251 Igf1
  mmu-miR-30e Igf1
  mmu-miR-344f-3p Igf1; Creb1
  mmu-miR-466l-5p Creb1; Igf1
  mmu-miR-709 Igf1
  mmu-miR-130a Creb1
  mmu-miR-202-5p Creb1
  mmu-miR-703 Creb1
Cell-cell signaling mmu-miR-883a-3p Gls
  mmu-miR-130a Lrp6
  mmu-miR-709 Lrp6
  mmu-miR-30e Myo5a; Lrp6
  mmu-miR-146b Myo5a
Lung development mmu-miR-344f-3p Igf1; Creb1
  mmu-miR-466l-5p Igf1
  mmu-miR-202-5p Creb1
  mmu-miR-703 Creb1
  mmu-miR-130a Creb1
  mmu-miR-1251 Foxp2; Igf1
  mmu-miR-3058 Igf1; Foxp2
  mmu-miR-490-5p Foxp2; Igf1
  mmu-miR-709 Foxp2; Igf1
  mmu-miR-669h-3p Foxp2; Igf1
  mmu-miR-30e Igf1
Wnt signaling pathway mmu-miR-669h-3p Apc
  mmu-miR-130a Lrp6
  mmu-miR-30e Lrp6
  mmu-miR-709 Myc; Lrp6
  mmu-miR-105 Usp34
  mmu-miR-669b-3p Mitf
Steroid metabolic process mmu-miR-30e Nr5a2
Angiogenesis mmu-miR-30e Pdcd10
  mmu-miR-202-5p Naa15
  mmu-miR-3085-5p Naa15
  mmu-miR-883a-3p Naa15
  mmu-miR-669h-3p Srpk2
Transforming growth factor beta receptor signaling pathway mmu-miR-130a Creb1
  mmu-miR-202-5p Creb1
  mmu-miR-344f-3p Creb1
  mmu-miR-703 Creb1
  1. Italicized data are upregulated by flutamide; boldface data are downregulated by flutamide