Table 9 Two-way ANOVA for univariate and pairwise comparisons between gender, estrous cycle stages, and exposure for NF-κB (p105/p50) expression
From: Sex-specific IL-6-associated signaling activation in ozone-induced lung inflammation
Univariate tests: dependent variable: NF-κB (p105/p50) | |||||||
|  |  |  | df | F | Sig. | Partial η2 | |
Analysis of gender and exposure | Exposure | FA | 1,52 | 37.382 | <0.0005 | 0.418 | |
Ozone | 1,52 | 287.977 | <0.0005 | 0.847 | |||
Sex | F | 1,52 | 341.072 | <0.0005 | 0.868 | ||
M | 1,52 | 21.306 | <0.0005 | 0.291 | |||
Analysis of female estrous cycle stages and exposure | Estrous cycle stage | Non-proestrus | 1,32 | 148.459 | <0.0005 | 0.823 | |
Proestrus | 1,32 | 89.059 | <0.0005 | 0.736 | |||
Exposure | FA | 1,32 | 3.581 | 0.068 | 0.101 | ||
Ozone | 1,32 | 0.731 | 0.399 | 0.022 | |||
Pairwise comparisons: dependent variable: NF-κB (p105/p50) | |||||||
|  |  |  | (I) Sex | (J) Sex | Mean difference (I–J) | 95 % CI for difference | |
Lower bound | Upper bound | ||||||
Analysis of gender and exposure | Exposure | FA | M | F | 0.349 | 0.235 | 0.464 |
Ozone | F | M | 0.970 | 0.855 | 1.085 | ||
Sex | F | Ozone | FA | 1.056 | 0.941 | 1.170 | |
M | FA | Ozone | 0.264 | 0.149 | 0.379 | ||
Analysis of female estrous cycle stages and exposure | Estrous cycle stage | Non-proestrus | Ozone | FA | 1.129 | 0.940 | 1.318 |
Proestrus | Ozone | FA | 0.874 | 0.686 | 1.063 | ||
Exposure | FA | Proestrus | Non-proestrus | 0.175 | 0.013 | 0.364 | |
Ozone | Non-proestrus | Proestrus | 0.079 | .110 | 0.268 | ||