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Table 9 Two-way ANOVA for univariate and pairwise comparisons between gender, estrous cycle stages, and exposure for NF-κB (p105/p50) expression

From: Sex-specific IL-6-associated signaling activation in ozone-induced lung inflammation

Univariate tests: dependent variable: NF-κB (p105/p50)
    df F Sig. Partial η2
Analysis of gender and exposure Exposure FA 1,52 37.382 <0.0005 0.418
Ozone 1,52 287.977 <0.0005 0.847
Sex F 1,52 341.072 <0.0005 0.868
M 1,52 21.306 <0.0005 0.291
Analysis of female estrous cycle stages and exposure Estrous cycle stage Non-proestrus 1,32 148.459 <0.0005 0.823
Proestrus 1,32 89.059 <0.0005 0.736
Exposure FA 1,32 3.581 0.068 0.101
Ozone 1,32 0.731 0.399 0.022
Pairwise comparisons: dependent variable: NF-κB (p105/p50)
    (I) Sex (J) Sex Mean difference (I–J) 95 % CI for difference
Lower bound Upper bound
Analysis of gender and exposure Exposure FA M F 0.349 0.235 0.464
Ozone F M 0.970 0.855 1.085
Sex F Ozone FA 1.056 0.941 1.170
M FA Ozone 0.264 0.149 0.379
Analysis of female estrous cycle stages and exposure Estrous cycle stage Non-proestrus Ozone FA 1.129 0.940 1.318
Proestrus Ozone FA 0.874 0.686 1.063
Exposure FA Proestrus Non-proestrus 0.175 0.013 0.364
Ozone Non-proestrus Proestrus 0.079 .110 0.268