Table 7 Two-way ANOVA for univariate and pairwise comparisons between gender, estrous cycle stages, and exposure for JAK2 expression
From: Sex-specific IL-6-associated signaling activation in ozone-induced lung inflammation
Univariate tests: dependent variable: JAK2 | |||||||
|  |  |  | df | F | Sig. | Partial η2 | |
Analysis of gender and exposure | Exposure | FA | 1, 52 | 0.890 | 0.350 | 0.017 | |
Ozone | 1, 52 | 1190.01 | <0.0005 | 0.958 | |||
Sex | F | 1, 52 | 972.745 | <0.0005 | 0.949 | ||
M | 1, 52 | 18.071 | <0.0005 | 0.258 | |||
Analysis of female estrous cycle stages and exposure | Estrous cycle stage | Non-proestrus | 1, 36 | 360.191 | <0.0005 | 0.909 | |
Proestrus | 1, 36 | 161.757 | <0.0005 | 0.818 | |||
Exposure | FA | 1, 36 | 147.012 | <0.0005 | 0.803 | ||
Ozone | 1, 36 | 34.392 | <0.0005 | 0.489 | |||
Pairwise comparisons: dependent variable: JAK2 | |||||||
|  |  |  | (I) Sex | (J) Sex | Mean difference (I–J) | 95 % CI for difference | |
Lower bound | Upper bound | ||||||
Analysis of gender and exposure | Exposure | FA | M | F | 0.065 | 0.074 | 0.205 |
Ozone | F | M | 2.395 | 2.255 | 2.534 | ||
Sex | F | Ozone | FA | 2.165 | 2.026 | 2.304 | |
M | FA | Ozone | 0.295 | 0.156 | 0.434 | ||
Analysis of female estrous cycle stages and exposure | Estrous cycle stage | Non-proestrus | Ozone | FA | 1.795 | 1.603 | 1.987 |
Proestrus | Ozone | FA | 1.203 | 1.011 | 1.395 | ||
Exposure | FA | Proestrus | Non-proestrus | 1.147 | 0.955 | 1.339 | |
Ozone | Proestrus | Non-proestrus | 0.555 | 0.363 | 0.747 | ||