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Table 7 Two-way ANOVA for univariate and pairwise comparisons between gender, estrous cycle stages, and exposure for JAK2 expression

From: Sex-specific IL-6-associated signaling activation in ozone-induced lung inflammation

Univariate tests: dependent variable: JAK2
    df F Sig. Partial η2
Analysis of gender and exposure Exposure FA 1, 52 0.890 0.350 0.017
Ozone 1, 52 1190.01 <0.0005 0.958
Sex F 1, 52 972.745 <0.0005 0.949
M 1, 52 18.071 <0.0005 0.258
Analysis of female estrous cycle stages and exposure Estrous cycle stage Non-proestrus 1, 36 360.191 <0.0005 0.909
Proestrus 1, 36 161.757 <0.0005 0.818
Exposure FA 1, 36 147.012 <0.0005 0.803
Ozone 1, 36 34.392 <0.0005 0.489
Pairwise comparisons: dependent variable: JAK2
    (I) Sex (J) Sex Mean difference (I–J) 95 % CI for difference
Lower bound Upper bound
Analysis of gender and exposure Exposure FA M F 0.065 0.074 0.205
Ozone F M 2.395 2.255 2.534
Sex F Ozone FA 2.165 2.026 2.304
M FA Ozone 0.295 0.156 0.434
Analysis of female estrous cycle stages and exposure Estrous cycle stage Non-proestrus Ozone FA 1.795 1.603 1.987
Proestrus Ozone FA 1.203 1.011 1.395
Exposure FA Proestrus Non-proestrus 1.147 0.955 1.339
Ozone Proestrus Non-proestrus 0.555 0.363 0.747