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Table 3 Two-way ANOVA for univariate and pairwise comparisons between gender, estrous cycle stages, and exposure for IL6R expression

From: Sex-specific IL-6-associated signaling activation in ozone-induced lung inflammation

Univariate tests: dependent variable: IL6R
    df F Sig. Partial η2
Analysis of gender and exposure Exposure FA 1, 52 4.275 0.044 0.076
Ozone 1, 52 44.137 <0.0005 0.459
Sex F 1, 52 70.840 <0.0005 0.577
M 1, 52 0.087 0.770 0.002
Analysis of female estrous cycle stages and exposure Estrous cycle stage Non-proestrus 1, 24 150.946 <0.0005 0.863
Proestrus 1, 24 141.524 <0.0005 0.855
Exposure FA 1, 24 10.240 0.004 0.299
Ozone 1, 24 7.898 0.010 0.248
Pairwise comparisons: dependent variable: IL6R
    (I) Sex (J) Sex Mean difference (I–J) 95 % CI for difference
Lower bound Upper bound
Analysis of gender and exposure Exposure FA M F 0.439 0.013 0.864
Ozone F M 1.409 0.984 1.835
Sex F Ozone FA 1.785 1.360 2.211
M FA Ozone 0.062 0.363 0.488
Analysis of female estrous cycle stages and exposure Estrous cycle stage Non-proestrus Ozone FA 2.529 2.104 2.954
Proestrus Ozone FA 2.449 2.024 2.874
Exposure FA Proestrus Non-proestrus 0.659 0.234 1.084
Ozone Proestrus Non-proestrus 0.579 0.154 1.003