Table 10 Two-way ANOVA for univariate and pairwise comparisons between gender, estrous cycle stages and exposure for AKT1 expression
From: Sex-specific IL-6-associated signaling activation in ozone-induced lung inflammation
Univariate tests: dependent variable: AKT1 | |||||||
|  |  |  | df | F | Sig. | Partial η2 | |
Analysis of gender and exposure | Exposure | FA | 1,52 | 0.001 | 0.996 | 0.002 | |
Ozone | 1,52 | 121.354 | <0.0005 | 0.700 | |||
Sex | F | 1,52 | 64.526 | <0.0005 | 0.554 | ||
M | 1,52 | 8.929 | 0.004 | 0.147 | |||
Analysis of female estrous cycle stages and exposure | Estrous cycle stage | Non-proestrus | 1,24 | 179.278 | <0.0005 | 0.882 | |
Proestrus | 1,24 | 511.045 | <0.0005 | 0.955 | |||
Exposure | FA | 1,24 | 3.261 | 0.084 | 0.120 | ||
Ozone | 1,24 | 54.923 | <0.0005 | 0.696 | |||
Pairwise comparisons: dependent variable: AKT1 | |||||||
|  |  |  | (I) Sex | (J) Sex | Mean difference (I–J) | 95 % CI for difference | |
Lower bound | Upper bound | ||||||
Analysis of gender and exposure | Exposure | FA | F | M | 0.001 | 0.167 | 0.168 |
Ozone | F | M | 0.919 | 0.751 | 1.086 | ||
Sex | F | Ozone | FA | 0.670 | 0.503 | 0.837 | |
M | FA | Ozone | 0.249 | 0.082 | 0.417 | ||
Analysis of female estrous cycle stages and exposure | Estrous cycle stage | Non-proestrus | Ozone | FA | 1.121 | 0.948 | 1.293 |
Proestrus | Ozone | FA | 1.892 | 1.719 | 2.065 | ||
Exposure | FA | Non-proestrus | Proestrus | 0.151 | 0.022 | 0.324 | |
Ozone | Proestrus | Non-proestrus | 0.620 | 0.448 | 0.793 | ||